8QPB

Cryo-EM Structure of Pre-B+ATP Complex (core part)

Summary for 8QPB

• Entry DOI: 10.2210/pdb8qpb/pdb
• EMDB information: 18547
• Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase, 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ... (18 entities in total)
• Functional Keywords: spliceosome, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 17
• Total formula weight: 1421310.52

Authors

Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-10-01, release date: 2024-05-22, Last modification date: 2024-06-05)

• Primary citation: Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Structural insights into the cross-exon to cross-intron spliceosome switch.; Nature, 2024; PubMed: 38778104; DOI: 10.1038/s41586-024-07458-1

Experimental method

ELECTRON MICROSCOPY (3.7 Å)