8UZH

SUMO fused Trehalose Synthase (TreS) of Mycobacterium tuberculosis

Summary for 8UZH

Entry DOI	10.2210/pdb8uzh/pdb
Descriptor	SUMO fused Trehalose Synthase (TreS),Trehalose synthase/amylase TreS, CALCIUM ION (3 entities in total)
Functional Keywords	tres, trehalose synthase, mycobacterium tuberculosis, cytosolic protein, sugar binding protein
Biological source	Saccharomyces cerevisiae More
Total number of polymer chains	2
Total formula weight	159194.27
Authors	Pathirage, R.,Ronning, D.R. (deposition date: 2023-11-15, release date: 2024-03-27, Last modification date: 2024-04-24)
Primary citation	Kalera, K.,Liu, R.,Lim, J.,Pathirage, R.,Swanson, D.H.,Johnson, U.G.,Stothard, A.I.,Lee, J.J.,Poston, A.W.,Woodruff, P.J.,Ronning, D.R.,Eoh, H.,Swarts, B.M. Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift. Acs Infect Dis., 10:1391-1404, 2024 Cited by PubMed: 38485491 DOI: 10.1021/acsinfecdis.4c00138 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation