Summary for 8QXD
Entry DOI | 10.2210/pdb8qxd/pdb |
EMDB information | 18718 |
Descriptor | Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein 4A, U5 small nuclear ribonucleoprotein 40 kDa protein, ... (51 entities in total) |
Functional Keywords | spliceosome, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 61 |
Total formula weight | 2649726.79 |
Authors | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-10-24, release date: 2024-05-22, Last modification date: 2024-06-05) |
Primary citation | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R. Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024 Cited by PubMed: 38778104DOI: 10.1038/s41586-024-07458-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (9.6 Å) |
Structure validation
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