PDB: 436 件ウェブページステータス検索Chemie searchBIRD

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3GF1	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY 分子名称: INSULIN-LIKE GROWTH FACTOR I 著者 Cooke, R.M, Harvey, T.S, Campbell, I.D. 登録日 1991-01-24 公開日 1993-04-15 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry, 30, 1991
3GKY	The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. 登録日 2009-03-11 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY. J.Biol.Chem., 284, 2009
3I3Z	Human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Cuprov-Netochin, R.N, Samigina, V.R, Kuranova, I.P. 登録日 2009-07-01 公開日 2010-01-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
3I40	Human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Chuprov-Netochin, R.N, Kuranova, I.P. 登録日 2009-07-01 公開日 2010-01-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
3ILG	Crystal structure of humnan insulin Sr+2 complex 分子名称: Insulin A chain, Insulin B chain, STRONTIUM ION 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-07 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
3INC	Crystal structure of human insulin with Ni+2 complex 分子名称: Insulin A chain, Insulin B chain, NICKEL (II) ION 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-12 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
3INS	STRUCTURE OF INSULIN. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT 分子名称: INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION 著者 Wlodawer, A, Savage, H. 登録日 1988-10-14 公開日 1989-01-09 最終更新日 2017-11-29 実験手法 NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION 主引用文献 Structure of insulin: results of joint neutron and X-ray refinement. Acta Crystallogr.,Sect.B, 45, 1989
3IR0	Crystal Structure of Human Insulin complexed with Cu+2 metal ion 分子名称: COPPER (II) ION, Insulin A chain, Insulin B chain 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-21 公開日 2010-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Metal induced structural changes observed in Human insulin To be Published
3JSD	Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. 登録日 2009-09-10 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus To be Published
3KQ6	Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Wan, Z.L, Hu, S.Q, Whittaker, L, Phillips, N.B, Whittake, J, Ismail-Beigi, F, Weiss, M.A. 登録日 2009-11-17 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot. J.Biol.Chem., 285, 2010
3KR3	Crystal structure of IGF-II antibody complex 分子名称: 1,2-ETHANEDIOL, Insulin-like growth factor II, antibody-Fab (heavy chain), ... 著者 Peat, T.S, Newman, J, Adams, T.E. 登録日 2009-11-17 公開日 2010-06-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo. Mol.Cancer Ther., 9, 2010
3LRI	Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I 分子名称: PROTEIN (INSULIN-LIKE GROWTH FACTOR I) 著者 Laajoki, L.G, Francis, G.L, Wallace, J.C, Carver, J.A, Keniry, M.A. 登録日 1999-04-13 公開日 2000-05-23 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I J.Biol.Chem., 275, 2000
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
3P2X	Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3P33	Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3Q6E	Human insulin in complex with cucurbit[7]uril 分子名称: Insulin A chain, Insulin B chain, cucurbit[7]uril 著者 Chinai, J.M, Taylor, A.B, Hargreaves, N.D, Ryno, L.M, Morris, C.A, Hart, P.J, Urbach, A.R. 登録日 2010-12-31 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular recognition of insulin by a synthetic receptor. J.Am.Chem.Soc., 133, 2011
3ROV	Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. 登録日 2011-04-26 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus To be Published
3RTO	Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure 分子名称: Insulin, ZINC ION 著者 Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
3T2A	TMAO-grown cubic insulin (porcine) 分子名称: Insulin A chain, Insulin B chain, trimethylamine oxide 著者 Cahn, J, Venkat, M, Marshall, H, Juers, D. 登録日 2011-07-22 公開日 2011-12-28 最終更新日 2012-01-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
3TT8	Crystal Structure Analysis of Cu Human Insulin Derivative 分子名称: COPPER (II) ION, INSULIN A-CHAIN, INSULIN B-CHAIN 著者 Prugovecki, B, Matkovic-Calogovic, D. 登録日 2011-09-14 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Crystal Structure Analysis of Cu Human Insulin Derivative To be Published
3U4N	A novel covalently linked insulin dimer 分子名称: Insulin A chain, Insulin B chain 著者 Norrman, M, Vinther, T.N. 登録日 2011-10-10 公開日 2012-04-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization. Plos One, 7, 2012
3V19	Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. 登録日 2011-12-09 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health To be Published
3V1G	Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. 登録日 2011-12-09 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health To be Published
3W11	Insulin receptor ectodomain construct comprising domains L1-CR in complex with human insulin, Alpha-CT peptide(704-719) and FAB 83-7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... 著者 Lawrence, M.C, Smith, B.J. 登録日 2012-11-06 公開日 2013-01-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
3W7Y	0.92A structure of 2Zn human insulin at 100K 分子名称: Insulin, ZINC ION 著者 Sakabe, N, Sakabe, K, Sasaki, K, Murayoshi, M. 登録日 2013-03-11 公開日 2013-07-03 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (0.92 Å) 主引用文献 0.92A structure of 2Zn human insulin at 100K To be Published

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