3ILG

Crystal structure of humnan insulin Sr+2 complex

Summary for 3ILG

Related1HYF 1G1S 2R36 2R34 2R35
DescriptorInsulin A chain, Insulin B chain, STRONTIUM ION, ... (4 entities in total)
Functional Keywordsinsulin, conformational state, metal binding, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11810.54
Authors
Raghavendra, N.,Pattabhi, V.,Rajan, S.S. (deposition date: 2009-08-07, release date: 2010-08-11, Last modification date: 2011-07-13)
Primary citation
Raghavendra, N.,Pattabhi, V.,Rajan, S.S.
Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin
To be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.272904.3%9.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution