Crystal structure of MN human arg-insulin

Summary for 2R34

Related1TRZ 2QIU 2R35 2R36
DescriptorInsulin, MANGANESE (II) ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordshormone, glucose utilisation, t3r3 conformation
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight12130.47
Sreekanth, R.,Pattabhi, V.,Rajan, S.S. (deposition date: 2007-08-29, release date: 2008-09-02, Last modification date: 2011-07-13)
Primary citation
Sreekanth, R.,Pattabhi, V.,Rajan, S.S.
Metal induced structural changes observed in hexameric insulin
Int.J.Biol.Macromol., 44:29-36, 2009
PubMed: 18977386 (PDB entries with the same primary citation)
DOI: 10.1016/j.ijbiomac.2008.09.019
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1911004.5%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution