2QIU

Structure of Human Arg-Insulin

Summary for 2QIU

Related1ZNI
DescriptorInsulin, ZINC ION, ... (4 entities in total)
Functional Keywordshormone, glucose utilisation, t3r3 conformation
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight12080.51
Authors
Sreekanth, R.,Pattabhi, V.,Rajan, S.S. (deposition date: 2007-07-05, release date: 2008-02-26, Last modification date: 2011-07-13)
Primary citation
Sreekanth, R.,Pattabhi, V.,Rajan, S.S.
Structural interpretation of reduced insulin activity as seen in the crystal structure of human Arg-insulin
Biochimie, 90:467-473, 2008
PubMed: 18029081 (PDB entries with the same primary citation)
DOI: 10.1016/j.biochi.2007.09.012
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2373508.5%8.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution