3U4N

A novel covalently linked insulin dimer

Summary for 3U4N

DescriptorInsulin A chain, Insulin B chain (3 entities in total)
Functional Keywordszn-free insulin with additional disulfide bond, hormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5672.52
Authors
Norrman, M.,Vinther, T.N. (deposition date: 2011-10-10, release date: 2012-04-11)
Primary citation
Vinther, T.N.,Norrman, M.,Strauss, H.M.,Huus, K.,Schlein, M.,Pedersen, T.A.,Kjeldsen, T.,Jensen, K.J.,Hubalek, F.
Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization.
Plos One, 7:e30882-e30882, 2012
PubMed: 22363506 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0030882
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.98 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2214000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution