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3INC

Crystal structure of human insulin with Ni+2 complex

Summary for 3INC
Entry DOI10.2210/pdb3inc/pdb
Related1MSO 1os4 2R34 2R35 2R36 3INS
DescriptorInsulin A chain, Insulin B chain, NICKEL (II) ION, ... (4 entities in total)
Functional Keywordsinsulin, conformational state, metal binding, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains4
Total formula weight11752.69
Authors
Raghavendra, N.,Pattabhi, V.,Rajan, S.S. (deposition date: 2009-08-12, release date: 2010-08-18, Last modification date: 2024-11-13)
Primary citationRaghavendra, N.,Pattabhi, V.,Rajan, S.S.
Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin
To be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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