3INC
Crystal structure of human insulin with Ni+2 complex
Summary for 3INC
Entry DOI | 10.2210/pdb3inc/pdb |
Related | 1MSO 1os4 2R34 2R35 2R36 3INS |
Descriptor | Insulin A chain, Insulin B chain, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | insulin, conformational state, metal binding, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 11752.69 |
Authors | Raghavendra, N.,Pattabhi, V.,Rajan, S.S. (deposition date: 2009-08-12, release date: 2010-08-18, Last modification date: 2024-11-13) |
Primary citation | Raghavendra, N.,Pattabhi, V.,Rajan, S.S. Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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