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8R55
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Bacillus subtilis MutS2-collided disome complex (collided 70S)
分子名称: 16S rRNA (1533-MER), 23S RNA (2887-MER), 30S ribosomal protein S10, ...
著者Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R.
登録日2023-11-16
公開日2024-01-17
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Embo J., 43, 2024
8A6W
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BU of 8a6w by Molmil
Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone
分子名称: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase
著者Snee, M, Amadi, C, Levy, C.
登録日2022-06-20
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone
To Be Published
6AO3
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BU of 6ao3 by Molmil
Crystal structure of the murine gasdermin D C-terminal domain
分子名称: Gasdermin-D
著者Liu, Z, Wang, C, Yang, J, Xiao, T.S.
登録日2017-08-15
公開日2018-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Structure, 26, 2018
1BU1
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BU of 1bu1 by Molmil
SRC FAMILY KINASE HCK SH3 DOMAIN
分子名称: PROTEIN (HEMOPOIETIC CELL KINASE)
著者Arold, S, Franken, P, Dumas, C.
登録日1998-09-09
公開日1998-11-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
Biochemistry, 37, 1998
6V65
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BU of 6v65 by Molmil
Crystal structure of KRAS(GMPPNP)-NF1(GRD)-SPRED1 complex
分子名称: FORMIC ACID, GTPase KRas, MAGNESIUM ION, ...
著者Yan, W, Simanshu, D.K.
登録日2019-12-04
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.763 Å)
主引用文献Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.
Cell Rep, 32, 2020
5J7K
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BU of 5j7k by Molmil
Loop grafting onto a highly stable FN3 scaffold
分子名称: FN3con-a-lys, ZINC ION
著者Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M.
登録日2016-04-06
公開日2016-08-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Circumventing the stability-function trade-off in an engineered FN3 domain.
Protein Eng.Des.Sel., 2016
1BUQ
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BU of 1buq by Molmil
SOLUTION STRUCTURE OF DELTA-5-3-KETOSTEROID ISOMERASE COMPLEXED WITH THE STEROID 19-NORTESTOSTERONE-HEMISUCCINATE
分子名称: PROTEIN (3-KETOSTEROID ISOMERASE-19-NORTESTOSTERONE-HEMISUCCINATE), SUCCINIC ACID MONO-(13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL) ESTER
著者Massiah, M.A, Abeygunawardana, C, Gittis, A.G, Mildvan, A.S.
登録日1998-09-04
公開日1999-01-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate.
Biochemistry, 37, 1998
6JBZ
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BU of 6jbz by Molmil
Structural analysis of molybdopterin synthases from two mycobacteria pathogens
分子名称: MoaD/ThiS family protein, Molybdenum cofactor biosynthesis protein E, SULFATE ION
著者Wang, H.Y, Liu, X.
登録日2019-01-27
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Structural analysis of molybdopterin synthases from two mycobacterial pathogens.
Biochem. Biophys. Res. Commun., 511, 2019
8G94
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BU of 8g94 by Molmil
Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi
分子名称: Early activation antigen CD69, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Chen, H, Li, X.
登録日2023-02-21
公開日2023-04-19
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Transmembrane protein CD69 acts as an S1PR1 agonist.
Elife, 12, 2023
6AQ7
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BU of 6aq7 by Molmil
Structure of POM6 FAB fragment complexed with mouse PrPc
分子名称: 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ...
著者Baral, P.K, Swayampakula, M, James, M.N.G.
登録日2017-08-18
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.
FEBS J., 285, 2018
8A9P
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BU of 8a9p by Molmil
Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment
分子名称: (3-phenyl-1,2,4-oxadiazol-5-yl)methanamine, BROMIDE ION, CHLORIDE ION, ...
著者Snee, M, Katariya, M, Levy, C, Leys, D.
登録日2022-06-29
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment
To Be Published
7KHP
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BU of 7khp by Molmil
Acyl-enzyme intermediate structure of SARS-CoV-2 Mpro in complex with its C-terminal autoprocessing sequence.
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE
著者Lee, J, Worrall, L.J, Paetzel, M, Strynadka, N.C.J.
登録日2020-10-21
公開日2020-10-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.
Nat Commun, 11, 2020
7ANU
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BU of 7anu by Molmil
Crystal structure of Pyrococcus abyssi Pbp11
分子名称: GLYCEROL, IMIDAZOLE, NICKEL (II) ION, ...
著者Hogrel, G, Girard, E, Franzetti, B.
登録日2020-10-12
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Characterization of a small tRNA-binding protein that interacts with the archaeal proteasome complex.
Mol.Microbiol., 118, 2022
7KJ7
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BU of 7kj7 by Molmil
Plasmodium falciparum protein Pf12p
分子名称: Surface protein P12p
著者Dietrich, M.H, Tham, W.H.
登録日2020-10-26
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
2IWG
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BU of 2iwg by Molmil
COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC
分子名称: 52 KDA RO PROTEIN, IG GAMMA-1 CHAIN C, alpha-L-fucopyranose, ...
著者James, L.C, Keeble, A.H, Rhodes, D.A, Trowsdale, J.
登録日2006-06-30
公開日2007-03-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Pryspry-Mediated Tripartite Motif (Trim) Protein Function.
Proc.Natl.Acad.Sci.USA, 104, 2007
7KOE
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BU of 7koe by Molmil
Electron bifurcating flavoprotein Fix/EtfABCX
分子名称: Electron transfer flavoprotein, alpha subunit, beta subunit, ...
著者Feng, X, Li, H.
登録日2020-11-08
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX.
Proc.Natl.Acad.Sci.USA, 118, 2021
7B1X
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BU of 7b1x by Molmil
Crystal structure of cold-active esterase PMGL3 from permafrost metagenomic library
分子名称: esterase PMGL3
著者Boyko, K.M, Nikolaeva, A.Y, Petrovskaya, L.E, Kryukova, M.V, Kryukova, E.A, Korzhenevsky, D.A, Lomakina, G.Y, Novototskaya-Vlasova, K.A, Rivkina, E.M, Dolgikh, D.A, Kirpichnikov, M.P, Popov, V.O.
登録日2020-11-25
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biochemical Characterization of a Cold-Active PMGL3 Esterase with Unusual Oligomeric Structure.
Biomolecules, 11, 2021
5JK7
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BU of 5jk7 by Molmil
The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex
分子名称: DNA damage-binding protein 1, Protein VPRBP, Protein Vpr, ...
著者Calero, G, Ahn, J, Wu, Y.
登録日2016-04-26
公開日2016-10-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol., 23, 2016
5JMC
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BU of 5jmc by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
分子名称: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
著者Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
登録日2016-04-28
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
7AIK
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BU of 7aik by Molmil
Ribonucleotide Reductase R2 protein from Aquifex aeolicus
分子名称: FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta,Ribonucleoside-diphosphate reductase subunit beta
著者Rehling, D, Scaletti, E.R, Stenmark, P.
登録日2020-09-27
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
5MCU
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BU of 5mcu by Molmil
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG2)
分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ...
著者Golovenko, D, Rozenberg, H, Shakked, Z.
登録日2016-11-10
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins.
Structure, 26, 2018
6SP2
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BU of 6sp2 by Molmil
CryoEM structure of SERINC from Drosophila melanogaster
分子名称: CARDIOLIPIN, Lauryl Maltose Neopentyl Glycol, Membrane protein TMS1d, ...
著者Pye, V.E, Nans, A, Cherepanov, P.
登録日2019-08-30
公開日2020-01-01
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献A bipartite structural organization defines the SERINC family of HIV-1 restriction factors.
Nat.Struct.Mol.Biol., 27, 2020
6BBA
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BU of 6bba by Molmil
Crystal structure of human mitochondrial ClpP complex with acyldepsipeptide ADEP-28
分子名称: ATP-dependent Clp protease proteolytic subunit, mitochondrial, Acyldepsipeptide ADEP-28
著者Mabanglo, M.F, Houry, W.A.
登録日2017-10-17
公開日2018-07-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Cell Chem Biol, 25, 2018
7ZZI
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BU of 7zzi by Molmil
Plasmodium falciparum hexokinase complexed with glucose and citrate
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Phosphotransferase, ...
著者Fritz-Wolf, K, Dillenberger, M, Rahlfs, S, Becker, K.
登録日2022-05-25
公開日2023-08-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium -Specific Insertion.
Int J Mol Sci, 24, 2023
8RZC
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BU of 8rzc by Molmil
SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 11
分子名称: 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanylmethyl]-5-imidazol-1-yl-benzoic acid, ...
著者Kalnins, G.
登録日2024-02-12
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 11
To Be Published

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件を2024-07-17に公開中

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