PDB: 2059 件ウェブページステータス検索Chemie searchBIRD

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3J81	CryoEM structure of a partial yeast 48S preinitiation complex 分子名称: 18S rRNA, MAGNESIUM ION, METHIONINE, ... 著者 Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. 登録日 2014-08-29 公開日 2014-11-05 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
7YDQ	Structure of PfNT1(Y190A)-GFP in complex with GSK4 分子名称: 5-methyl-N-[2-(2-oxidanylideneazepan-1-yl)ethyl]-2-phenyl-1,3-oxazole-4-carboxamide, Nucleoside transporter 1,Green fluorescent protein 著者 Wang, C, Yu, L.Y, Li, J.L, Ren, R.B, Deng, D. 登録日 2022-07-04 公開日 2023-04-26 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.04 Å) 主引用文献 Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023
7E2I	Cryo-EM structure of hDisp1NNN-ShhN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1, ... 著者 Li, W, Wang, L, Gong, X. 登録日 2021-02-05 公開日 2021-12-08 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nat Commun, 12, 2021
8A43	Human RNA polymerase I 分子名称: DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... 著者 Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. 登録日 2022-06-10 公開日 2022-08-31 最終更新日 2022-11-02 実験手法 ELECTRON MICROSCOPY (4.09 Å) 主引用文献 The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. Life Sci Alliance, 5, 2022
7NWH	Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
8HCO	Substrate-engaged TOM complex from yeast 分子名称: Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, Mitochondrial import receptor subunit TOM5, ... 著者 Zhou, X.Y, Yang, Y.Q, Wang, G.P, Wang, S.S. 登録日 2022-11-02 公開日 2023-09-13 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Molecular pathway of mitochondrial preprotein import through the TOM-TIM23 supercomplex. Nat.Struct.Mol.Biol., 30, 2023
6G51	Cryo-EM structure of a late human pre-40S ribosomal subunit - State D 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
8DN4	Cryo-EM structure of human Glycine Receptor alpha-1 beta heteromer, glycine-bound state3(desensitized state) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-1, Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta, ... 著者 Liu, X, Wang, W. 登録日 2022-07-10 公開日 2023-10-11 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Asymmetric gating of a human hetero-pentameric glycine receptor. Nat Commun, 14, 2023
6LQQ	Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Ye, K. 登録日 2020-01-14 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
7KAP	Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 1 (C1) 分子名称: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... 著者 Itskanov, S, Park, E. 登録日 2020-10-01 公開日 2021-01-06 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62. Nat.Struct.Mol.Biol., 28, 2021
7AA5	Human TRPV4 structure in presence of 4a-PDD 分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein 著者 Botte, M, Ulrich, A.K.G, Adaixo, R, Gnutt, D, Brockmann, A, Bucher, D, Chami, M, Bocquet, M, Ebbinghaus-Kintscher, U, Puetter, V, Becker, A, Egner, U, Stahlberg, H, Hennig, M, Holton, S.J. 登録日 2020-09-03 公開日 2021-08-18 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation To Be Published
6SW9	IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Coureux, P.-D, Mechulam, Y, Schmitt, E. 登録日 2019-09-20 公開日 2020-02-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
6XIQ	Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress 分子名称: 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Zhou, Y, Bartesaghi, A, Silva, G.M. 登録日 2020-06-21 公開日 2020-08-26 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
5OA3	Human 40S-eIF2D-re-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N. 登録日 2017-06-20 公開日 2017-08-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural and Functional Insights into Human Re-initiation Complexes. Mol. Cell, 67, 2017
7SYK	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII) 分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... 著者 Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. 登録日 2021-11-25 公開日 2022-07-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
5JUS	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure III (mid-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5H8O	Crystal structure of an ASC-binding nanobody in complex with the CARD domain of ASC 分子名称: Apoptosis-associated speck-like protein containing a CARD, VHH nanobody 著者 Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L. 登録日 2015-12-23 公開日 2016-04-06 最終更新日 2016-05-18 実験手法 X-RAY DIFFRACTION (4.206 Å) 主引用文献 A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. J.Exp.Med., 213, 2016
4V8Y	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex 分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... 著者 Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. 登録日 2013-07-20 公開日 2014-07-09 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
7ZUW	Structure of RQT (C1) bound to the stalled ribosome in a disome unit from S. cerevisiae 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. 登録日 2022-05-13 公開日 2023-02-22 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
7SYG	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) 分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... 著者 Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. 登録日 2021-11-25 公開日 2022-07-13 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
7K17	Re-refined crystal structure of DNA-dependent protein kinase catalytic subunit complexed with Ku80 C-terminal helix 分子名称: DNA-dependent protein kinase catalytic subunit, X-ray repair cross-complementing protein 5 著者 Chen, X, Gellert, M, Yang, W. 登録日 2020-09-07 公開日 2021-01-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
7NRD	Structure of the yeast Gcn1 bound to a colliding stalled 80S ribosome with MBF1, A/P-tRNA and P/E-tRNA 分子名称: 25S rRNA (3184-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Pochopien, A.A, Beckert, B, Wilson, D.N. 登録日 2021-03-03 公開日 2021-04-14 実験手法 ELECTRON MICROSCOPY (4.36 Å) 主引用文献 Structure of Gcn1 bound to stalled and colliding 80S ribosomes. Proc.Natl.Acad.Sci.USA, 118, 2021
7RFP	Mouse GITR (mGITR) with DTA-1 Fab fragment 分子名称: DTA-1 (heavy chain), DTA-1 (light chain), Tumor necrosis factor receptor superfamily member 18,Enhanced green fluorescent protein 著者 Meyerson, J.R, He, C. 登録日 2021-07-14 公開日 2022-03-09 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism. Sci Adv, 8, 2022
6GQ1	Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y. 登録日 2018-06-07 公開日 2018-07-11 最終更新日 2018-08-08 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
7SYT	Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) 分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... 著者 Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. 登録日 2021-11-25 公開日 2022-07-13 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022

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