7K17

Re-refined crystal structure of DNA-dependent protein kinase catalytic subunit complexed with Ku80 C-terminal helix

Summary for 7K17

• Entry DOI: 10.2210/pdb7k17/pdb
• Related: 7K0Y
• Descriptor: DNA-dependent protein kinase catalytic subunit, X-ray repair cross-complementing protein 5 (2 entities in total)
• Functional Keywords: nhej, v(d)j recombination, dna repair, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 947941.00

Authors

Chen, X.,Gellert, M.,Yang, W. (deposition date: 2020-09-07, release date: 2021-01-06, Last modification date: 2023-10-18)

• Primary citation: Chen, X.,Xu, X.,Chen, Y.,Cheung, J.C.,Wang, H.,Jiang, J.,de Val, N.,Fox, T.,Gellert, M.,Yang, W.; Structure of an activated DNA-PK and its implications for NHEJ.; Mol.Cell, 81:801-810.e3, 2021; PubMed: 33385326; DOI: 10.1016/j.molcel.2020.12.015

Experimental method

X-RAY DIFFRACTION (4.3 Å)