CryoEM structure of a partial yeast 48S preinitiation complex

Summary for 3J81

EMDB information2763
Descriptor18S rRNA, uS2, eS1, ... (45 entities in total)
Functional Keywordseukaryotic translation initiation, 48s, small ribosome subunit, ribosome
Biological sourceSaccharomyces cerevisiae (yeast)
Total number of polymer chains42
Total molecular weight1364522.89
Hussain, T.,Llacer, J.L.,Fernandez, I.S.,Savva, C.G.,Ramakrishnan, V. (deposition date: 2014-08-29, release date: 2014-11-05, Last modification date: 2018-07-18)
Primary citation
Hussain, T.,Llacer, J.L.,Fernandez, I.S.,Munoz, A.,Martin-Marcos, P.,Savva, C.G.,Lorsch, J.R.,Hinnebusch, A.G.,Ramakrishnan, V.
Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159:597-607, 2014
PubMed: 25417110 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2014.10.001
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone84.9%12.1%0.33MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload