Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3J81

CryoEM structure of a partial yeast 48S preinitiation complex

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000054	biological_process	ribosomal subunit export from nucleus
a	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0003729	molecular_function	mRNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0022627	cellular_component	cytosolic small ribosomal subunit
a	0030686	cellular_component	90S preribosome
a	0046872	molecular_function	metal ion binding
a	1990904	cellular_component	ribonucleoprotein complex
A	0000028	biological_process	ribosomal small subunit assembly
A	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0003735	molecular_function	structural constituent of ribosome
A	0005737	cellular_component	cytoplasm
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0015935	cellular_component	small ribosomal subunit
A	0022627	cellular_component	cytosolic small ribosomal subunit
A	1990904	cellular_component	ribonucleoprotein complex
b	0000028	biological_process	ribosomal small subunit assembly
b	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0008270	molecular_function	zinc ion binding
b	0022627	cellular_component	cytosolic small ribosomal subunit
b	0046872	molecular_function	metal ion binding
b	1990904	cellular_component	ribonucleoprotein complex
B	0003735	molecular_function	structural constituent of ribosome
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
c	0000028	biological_process	ribosomal small subunit assembly
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0022627	cellular_component	cytosolic small ribosomal subunit
c	0030490	biological_process	maturation of SSU-rRNA
c	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0015935	cellular_component	small ribosomal subunit
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	0046872	molecular_function	metal ion binding
C	1990904	cellular_component	ribonucleoprotein complex
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0008270	molecular_function	zinc ion binding
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005634	cellular_component	nucleus
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0022626	cellular_component	cytosolic ribosome
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0022627	cellular_component	cytosolic small ribosomal subunit
e	1990904	cellular_component	ribonucleoprotein complex
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0008270	molecular_function	zinc ion binding
f	0031386	molecular_function	protein tag activity
f	0046872	molecular_function	metal ion binding
f	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0015935	cellular_component	small ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
g	0005092	molecular_function	GDP-dissociation inhibitor activity
g	0006417	biological_process	regulation of translation
g	0007186	biological_process	G protein-coupled receptor signaling pathway
g	0043022	molecular_function	ribosome binding
g	0045182	molecular_function	translation regulator activity
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	1990904	cellular_component	ribonucleoprotein complex
h	0002181	biological_process	cytoplasmic translation
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	1990904	cellular_component	ribonucleoprotein complex
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006364	biological_process	rRNA processing
H	0006412	biological_process	translation
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0030686	cellular_component	90S preribosome
H	0032040	cellular_component	small-subunit processome
H	0042274	biological_process	ribosomal small subunit biogenesis
H	1990904	cellular_component	ribonucleoprotein complex
i	0001677	biological_process	formation of translation initiation ternary complex
i	0001731	biological_process	formation of translation preinitiation complex
i	0001732	biological_process	formation of cytoplasmic translation initiation complex
i	0002188	biological_process	translation reinitiation
i	0003723	molecular_function	RNA binding
i	0003725	molecular_function	double-stranded RNA binding
i	0003743	molecular_function	translation initiation factor activity
i	0005515	molecular_function	protein binding
i	0005737	cellular_component	cytoplasm
i	0006412	biological_process	translation
i	0006413	biological_process	translational initiation
i	0010494	cellular_component	cytoplasmic stress granule
i	0016282	cellular_component	eukaryotic 43S preinitiation complex
i	0019901	molecular_function	protein kinase binding
i	0031369	molecular_function	translation initiation factor binding
i	0033290	cellular_component	eukaryotic 48S preinitiation complex
i	0043024	molecular_function	ribosomal small subunit binding
I	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	1990904	cellular_component	ribonucleoprotein complex
j	0001731	biological_process	formation of translation preinitiation complex
j	0003676	molecular_function	nucleic acid binding
j	0003723	molecular_function	RNA binding
j	0003743	molecular_function	translation initiation factor activity
j	0005515	molecular_function	protein binding
j	0005525	molecular_function	GTP binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
j	0006412	biological_process	translation
j	0006413	biological_process	translational initiation
j	0010494	cellular_component	cytoplasmic stress granule
j	0033290	cellular_component	eukaryotic 48S preinitiation complex
j	0043022	molecular_function	ribosome binding
j	0043614	cellular_component	multi-eIF complex
j	1990856	molecular_function	methionyl-initiator methionine tRNA binding
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0019843	molecular_function	rRNA binding
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0032040	cellular_component	small-subunit processome
J	0042274	biological_process	ribosomal small subunit biogenesis
J	1990904	cellular_component	ribonucleoprotein complex
k	0000049	molecular_function	tRNA binding
k	0000166	molecular_function	nucleotide binding
k	0001731	biological_process	formation of translation preinitiation complex
k	0003743	molecular_function	translation initiation factor activity
k	0003924	molecular_function	GTPase activity
k	0005515	molecular_function	protein binding
k	0005525	molecular_function	GTP binding
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
k	0006412	biological_process	translation
k	0006413	biological_process	translational initiation
k	0016282	cellular_component	eukaryotic 43S preinitiation complex
k	0016787	molecular_function	hydrolase activity
k	0031369	molecular_function	translation initiation factor binding
k	0033290	cellular_component	eukaryotic 48S preinitiation complex
k	0043614	cellular_component	multi-eIF complex
k	0045903	biological_process	positive regulation of translational fidelity
k	1990856	molecular_function	methionyl-initiator methionine tRNA binding
K	0000054	biological_process	ribosomal subunit export from nucleus
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005737	cellular_component	cytoplasm
K	0005840	cellular_component	ribosome
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0034198	biological_process	cellular response to amino acid starvation
K	1990904	cellular_component	ribonucleoprotein complex
l	0001731	biological_process	formation of translation preinitiation complex
l	0003729	molecular_function	mRNA binding
l	0003743	molecular_function	translation initiation factor activity
l	0005515	molecular_function	protein binding
l	0005525	molecular_function	GTP binding
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
l	0006412	biological_process	translation
l	0006413	biological_process	translational initiation
l	0008270	molecular_function	zinc ion binding
l	0016282	cellular_component	eukaryotic 43S preinitiation complex
l	0031369	molecular_function	translation initiation factor binding
l	0043614	cellular_component	multi-eIF complex
l	0046872	molecular_function	metal ion binding
l	1990856	molecular_function	methionyl-initiator methionine tRNA binding
L	0000028	biological_process	ribosomal small subunit assembly
L	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0019843	molecular_function	rRNA binding
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
m	0001731	biological_process	formation of translation preinitiation complex
m	0003723	molecular_function	RNA binding
m	0003743	molecular_function	translation initiation factor activity
m	0005515	molecular_function	protein binding
m	0006412	biological_process	translation
m	0006413	biological_process	translational initiation
m	0006417	biological_process	regulation of translation
m	0006450	biological_process	regulation of translational fidelity
m	0016282	cellular_component	eukaryotic 43S preinitiation complex
m	0031369	molecular_function	translation initiation factor binding
m	0043024	molecular_function	ribosomal small subunit binding
m	0043614	cellular_component	multi-eIF complex
m	1990145	biological_process	maintenance of translational fidelity
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005730	cellular_component	nucleolus
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0070181	molecular_function	small ribosomal subunit rRNA binding
N	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0032040	cellular_component	small-subunit processome
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0000028	biological_process	ribosomal small subunit assembly
R	0003735	molecular_function	structural constituent of ribosome
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	1990904	cellular_component	ribonucleoprotein complex
S	0000054	biological_process	ribosomal subunit export from nucleus
S	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
S	0003676	molecular_function	nucleic acid binding
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	0046872	molecular_function	metal ion binding
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0000054	biological_process	ribosomal subunit export from nucleus
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0042274	biological_process	ribosomal small subunit biogenesis
T	0046872	molecular_function	metal ion binding
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015935	cellular_component	small ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006364	biological_process	rRNA processing
V	0006412	biological_process	translation
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0015935	cellular_component	small ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0005840	cellular_component	ribosome
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1801

Chain	Residue
2	G361
2	G362

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 1802

Chain	Residue
2	A93
2	G95
2	C401
2	G402
E	ARG3

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1803

Chain	Residue
2	A554
2	A555
2	G551
2	G552

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1804

Chain	Residue
2	A100
2	C360

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1805

Chain	Residue
2	G623
2	A1024

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1806

Chain	Residue
2	C582

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1807

Chain	Residue
2	C49

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1809

Chain	Residue
2	G1329
2	C1418

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1810

Chain	Residue
2	A11

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1811

Chain	Residue
2	U927
2	A928

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 1812

Chain	Residue
2	A1760
2	A1761
2	G1766
2	U1769
2	C1782

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1813

Chain	Residue
2	G548

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1814

Chain	Residue
2	A400

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1815

Chain	Residue
2	G16

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 1816

Chain	Residue
2	G361
2	G362
2	G376
2	A377
2	U378

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1817

Chain	Residue
2	A28
2	U29

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1818

Chain	Residue
2	G370
2	A604
2	G606

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1819

Chain	Residue
2	A997
2	U1003

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1820

Chain	Residue
2	C426
2	G428

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1821

Chain	Residue
2	U44
2	A47

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 1822

Chain	Residue
2	U1759
2	A1760
2	A1761
2	G1765
2	G1766

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1823

Chain	Residue
2	A618
2	A619
2	A620

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1825

Chain	Residue
2	A618

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1826

Chain	Residue
2	C1326
2	G1327
2	G1329

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1827

Chain	Residue
2	A622

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1828

Chain	Residue
2	C99
2	A100
2	U101
2	C360

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1830

Chain	Residue
2	G1108
2	G1109

site_id	DC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1831

Chain	Residue
2	U1768

site_id	DC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1832

Chain	Residue
2	G95

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1833

Chain	Residue
2	G1670
2	G1671
2	C1672
2	U1726

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1834

Chain	Residue
2	U1628
2	G1791

site_id	DC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1836

Chain	Residue
2	G458
2	A459
2	G460

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1837

Chain	Residue
2	G466
2	A467

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1838

Chain	Residue
2	A622
2	C624
2	U1030

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1839

Chain	Residue
2	G984
2	G1013

site_id	DC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1840

Chain	Residue
2	G1416

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1842

Chain	Residue
2	A104
2	C353

site_id	EC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1843

Chain	Residue
2	A1064

site_id	EC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1845

Chain	Residue
2	G403
2	C404
2	G422

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1846

Chain	Residue
2	U1302

site_id	EC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1847

Chain	Residue
2	A978

site_id	EC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1848

Chain	Residue
2	U58

site_id	EC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1849

Chain	Residue
2	A760

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1850

Chain	Residue
2	G1139

site_id	EC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1851

Chain	Residue
2	C826
2	U842

site_id	FC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1852

Chain	Residue
2	C530
2	A514
2	C529

site_id	FC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1853

Chain	Residue
2	U1301

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1855

Chain	Residue
2	G937

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1856

Chain	Residue
2	G1010

site_id	FC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1857

Chain	Residue
2	A212
2	G213

site_id	FC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1858

Chain	Residue
2	G1538
2	G1539

site_id	FC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1860

Chain	Residue
2	G1636

site_id	FC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1863

Chain	Residue
2	U1008
O	LYS129

site_id	FC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1866

Chain	Residue
2	G884
2	G924

site_id	GC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1868

Chain	Residue
2	C1158
2	U1282

site_id	GC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1869

Chain	Residue
2	A1467
2	A1473
2	G1539

site_id	GC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1870

Chain	Residue
2	G1443
2	A1444

site_id	GC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1871

Chain	Residue
2	G1175
2	C1455

site_id	GC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1872

Chain	Residue
2	G1198
2	G1200

site_id	GC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1873

Chain	Residue
2	C1429

site_id	GC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1874

Chain	Residue
2	C1196
2	C1463

site_id	GC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1875

Chain	Residue
2	U1268

site_id	GC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1876

Chain	Residue
2	G1272
2	C1273
2	G1426

site_id	HC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1877

Chain	Residue
2	G1537
2	G1539

site_id	HC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1878

Chain	Residue
2	G1482
2	U1520

site_id	HC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1879

Chain	Residue
2	C1273
2	G1426
2	G1427
i	ARG14

site_id	HC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1880

Chain	Residue
2	A1201
2	A1202

site_id	HC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG G 301

Chain	Residue
2	U64
2	A168
G	GLN176

site_id	HC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN a 500

Chain	Residue
a	CYS23
a	ASN25
a	CYS26
a	CYS74
a	CYS77

site_id	HC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN b 101

Chain	Residue
b	GLY39

site_id	HC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN f 501

Chain	Residue
f	CYS121
f	CYS124
f	CYS139
f	CYS142
f	PHE146

site_id	HC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MET k 601

Chain	Residue
1	A76
k	GLY141
k	TYR142
k	ALA143
k	GLU383

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIVkhT

Chain	Residue	Details
F	GLU93-THR119

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAH

Chain	Residue	Details
W	GLY100-HIS117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD

Chain	Residue	Details
O	LEU102-ASP124

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
X	LYS62-ARG69

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS

Chain	Residue	Details
L	GLY120-SER132

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
f	LYS27-ASP52

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKvfnqveIrpemVGhyLGEFsiT

Chain	Residue	Details
P	ASN98-THR122

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL

Chain	Residue	Details
Q	GLY71-LEU89

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
N	VAL98-TYR128

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWmLdK

Chain	Residue	Details
E	HIS8-LYS22

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. YGggKStGFGlVYNSvadakkfE

Chain	Residue	Details
Y	TYR64-GLU86

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfadGfLihSgqpVndfIEtatrhvlLrqGvlG

Chain	Residue	Details
D	ALA147-GLY183

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. IAGGnDkqGfPM

Chain	Residue	Details
G	ILE52-MET63

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI

Chain	Residue	Details
C	GLY98-ILE130

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PhkhvdaSgsInRkVLQsLE

Chain	Residue	Details
T	PRO90-GLU109

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI

Chain	Residue	Details
J	LEU105-ILE129

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ

Chain	Residue	Details
S	ARG123-GLN136

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. AVSAswDkTLRLWNL

Chain	Residue	Details
g	ALA81-LEU95
g	ILE123-THR137
g	ALA218-LEU232

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IqSKrLRNkIAGYtTH

Chain	Residue	Details
R	ILE41-HIS56

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCISCAIH

Chain	Residue	Details
a	TYR73-HIS80

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH

Chain	Residue	Details
H	LYS76-HIS89

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
c	GLU58-LEU66

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAARVHLG

Chain	Residue	Details
A	ALA14-GLY25

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEssyvNIP

Chain	Residue	Details
A	PRO118-PRO142

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
V	LEU11-ALA19

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStvLctPtG

Chain	Residue	Details
b	LYS36-GLY68

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALKvvLrtSlvhDGLarGL

Chain	Residue	Details
M	ALA20-LEU38

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL

Chain	Residue	Details
B	LEU61-LEU73

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RaaTGAkraqf.RkKrKfELG

Chain	Residue	Details
I	ARG11-GLY30

site_id	PS01262
Number of Residues	23
Details	IF1A Eukaryotic initiation factor 1A signature. MlGnGRveasCfDGnkRmaHIrG

Chain	Residue	Details
i	MET41-GLY63

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03015","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	98
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	40
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	21
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	74
Details	Domain: {"description":"S1-like"}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	11
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	71
Details	Domain: {"description":"S1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00180","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by GCN2","evidences":[{"source":"PubMed","id":"10733573","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1739968","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8336737","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30475211","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)