Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure III (mid-rotated 40S subunit)

This is a large structure.

Summary for 5JUS

Related5JUO 5JUP 5JUT 5JUU
EMDB information6645 6650 6644 6649 6643 6658 6646 6652 6647 6653
Descriptor18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... (86 entities in total)
Functional Keywords80s-ires, eef2, translocation, sordarin, ribosome
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains83
Total molecular weight3340490.76
Abeyrathne, P.,Koh, C.S.,Grant, T.,Grigorieff, N.,Korostelev, A.A. (deposition date: 2016-05-10, release date: 2016-10-05, Last modification date: 2019-11-27)
Primary citation
Abeyrathne, P.D.,Koh, C.S.,Grant, T.,Grigorieff, N.,Korostelev, A.A.
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5:-, 2016
PubMed: 27159452 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.14874
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone34 5.7% 9.2% 0.46MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report