7AA5

Human TRPV4 structure in presence of 4a-PDD

Summary for 7AA5

• Entry DOI: 10.2210/pdb7aa5/pdb
• EMDB information: 11690
• Descriptor: Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein, CALCIUM ION (2 entities in total)
• Functional Keywords: ion channel. open-conformation, agonist, 4a-pdd, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 425007.36

Authors

Botte, M.,Ulrich, A.K.G.,Adaixo, R.,Gnutt, D.,Brockmann, A.,Bucher, D.,Chami, M.,Bocquet, M.,Ebbinghaus-Kintscher, U.,Puetter, V.,Becker, A.,Egner, U.,Stahlberg, H.,Hennig, M.,Holton, S.J. (deposition date: 2020-09-03, release date: 2021-08-18)

• Primary citation: Botte, M.,Ulrich, A.K.G.,Adaixo, R.,Gnutt, D.,Brockmann, A.,Bucher, D.,Chami, M.,Bocquet, M.,Ebbinghaus-Kintscher, U.,Puetter, V.,Becker, A.,Egner, U.,Stahlberg, H.,Hennig, M.,Holton, S.J.; Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.18 Å)