7E2I

Cryo-EM structure of hDisp1NNN-ShhN

Summary for 7E2I

Entry DOI	10.2210/pdb7e2i/pdb
Related	7E2G 7E2H
EMDB information	30956 30957 30958
Descriptor	Sonic hedgehog protein, Protein dispatched homolog 1, ZINC ION, ... (5 entities in total)
Functional Keywords	membrane protein, lipid transport
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	225143.59
Authors	Li, W.,Wang, L.,Gong, X. (deposition date: 2021-02-05, release date: 2021-12-08)
Primary citation	Li, W.,Wang, L.,Wierbowski, B.M.,Lu, M.,Dong, F.,Liu, W.,Li, S.,Wang, P.,Salic, A.,Gong, X. Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nat Commun, 12:6966-6966, 2021 Cited by PubMed: 34845226 DOI: 10.1038/s41467-021-27257-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.07 Å)

Structure validation