7E2H

Cryo-EM structure of hDisp1NNN-3C-Cleavage

Summary for 7E2H

• Entry DOI: 10.2210/pdb7e2h/pdb
• Related: 7E2G 7E2I
• EMDB information: 30956 30957 30958
• Descriptor: Protein dispatched homolog 1, CHOLESTEROL HEMISUCCINATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: membrane protein, lipid transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 174703.85

Authors

Li, W.,Wang, L.,Gong, X. (deposition date: 2021-02-05, release date: 2021-12-08)

• Primary citation: Li, W.,Wang, L.,Wierbowski, B.M.,Lu, M.,Dong, F.,Liu, W.,Li, S.,Wang, P.,Salic, A.,Gong, X.; Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.; Nat Commun, 12:6966-6966, 2021; PubMed: 34845226; DOI: 10.1038/s41467-021-27257-w

Experimental method

ELECTRON MICROSCOPY (3.68 Å)