7E2H
Cryo-EM structure of hDisp1NNN-3C-Cleavage
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Protein dispatched homolog 1 | polymer | 270 | 29497.6 | 1 | UniProt (Q96F81) | Homo sapiens (Human) | |
| 2 | B (E) | Protein dispatched homolog 1 | polymer | 1248 | 140427.6 | 1 | UniProt (Q96F81) Pfam (PF02460) | Homo sapiens (Human) | |
| 3 | C, D, E, F, G... (E) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 8 | Chemie (Y01) | |||
| 4 | K, L, M, N (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
D: 1 - 262 (UniProt: Q96F81)
E: 281 - 1524 (UniProt: Q96F81)
| PDB | External Database | Details |
|---|---|---|
| Ser 263 | - | linker |
| Ser 264 | - | linker |
| Leu 271 | - | linker |
| Glu 272 | - | linker |
| Val 273 | - | linker |
| Leu 274 | - | linker |
| Phe 275 | - | linker |
| Gln 276 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 277 | - | linker |
| Pro 278 | - | linker |
| Gly 279 | - | linker |
| Ser 280 | - | linker |
| Asn 572 | Asp 572 | engineered mutation |
| Asn 573 | Asp 573 | engineered mutation |
| Asn 1051 | Asp 1051 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 169925.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4778.6 | |
| All* | Total formula weight | 174703.9 |
