7SYG

Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII)

Summary for 7SYG

• Entry DOI: 10.2210/pdb7syg/pdb
• Related: 7SYH 7SYI 7SYJ 7SYK 7SYL 7SYM 7SYN 7SYO 7SYP 7SYQ 7SYR 7SYS 7SYT 7SYU 7SYV 7SYW 7SYX
• EMDB information: 25527 25528 25529 25530 25531 25532 25533 25534 25535 25536 25537 25538 25539 25540 25541 25542 25543 25544 25545 25546 25547 25548 25549 25550 25551 25552 25553 25554 25555 25556 25557 25588 25589 25590 25591 25592 25593 25594 25595 25596 25597 25598 25599 25600 25601 25602 25603 25604
• Descriptor: 18S rRNA, eS8, uS4, ... (37 entities in total)
• Functional Keywords: hcv, ires, 40s, ribosome
• Biological source: Hepatitis C virus (isolate 1); More
• Total number of polymer chains: 36
• Total formula weight: 1389783.22

Authors

Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. (deposition date: 2021-11-25, release date: 2022-07-13, Last modification date: 2024-02-28)

• Primary citation: Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J.; Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.3 Å)