7RFP

Mouse GITR (mGITR) with DTA-1 Fab fragment

Summary for 7RFP

• Entry DOI: 10.2210/pdb7rfp/pdb
• EMDB information: 24444
• Descriptor: Tumor necrosis factor receptor superfamily member 18,Enhanced green fluorescent protein, DTA-1 (heavy chain), DTA-1 (light chain) (3 entities in total)
• Functional Keywords: mouse glucocorticoid-induced tumor necrosis factor receptor, mgitr, tnf receptor, dta-1, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 6
• Total formula weight: 264365.83

Authors

Meyerson, J.R.,He, C. (deposition date: 2021-07-14, release date: 2022-03-09)

• Primary citation: He, C.,Maniyar, R.R.,Avraham, Y.,Zappasodi, R.,Rusinova, R.,Newman, W.,Heath, H.,Wolchok, J.D.,Dahan, R.,Merghoub, T.,Meyerson, J.R.; Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism.; Sci Adv, 8:eabm4552-eabm4552, 2022; PubMed: 35213218; DOI: 10.1126/sciadv.abm4552

Experimental method

ELECTRON MICROSCOPY (4.4 Å)