7RFP

Mouse GITR (mGITR) with DTA-1 Fab fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tumor necrosis factor receptor superfamily member 18,Enhanced green fluorescent protein	polymer	490	54848.2	2	UniProt (O35714) UniProt (A0A7G8ZY66)	Mus musculus (Mouse)	Glucocorticoid-induced TNFR-related protein
2	C, E (H, I)	DTA-1 (heavy chain)	polymer	465	51014.6	2		Mus musculus (Mouse)
3	D, F (L, M)	DTA-1 (light chain)	polymer	240	26320.1	2		Mus musculus (Mouse)

Sequence modifications

A, B: 1 - 228 (UniProt: O35714)

PDB	External Database	Details
Ala 229	-	linker
Gly 230	-	linker
Leu 231	-	linker
Val 232	-	linker
Pro 233	-	linker
Arg 234	-	linker
Gly 235	-	linker
Ser 236	-	linker
Ala 237	-	linker
Ala 238	-	linker
Ala 239	-	linker

A, B: 240 - 482 (UniProt: A0A7G8ZY66)

PDB	External Database	Details
Lys 446	Ala 207	conflict
His 483	-	expression tag
His 484	-	expression tag
His 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	264365.8
All*	Total formula weight	264365.8

*Water molecules are not included.