PDB: 375 件ウェブページステータス検索Chemie searchBIRD

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6PB4	The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.35 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB6	The E. coli class-II CAP-dependent transcription activation complex at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.29 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
3OTF	Structural basis for the cAMP-dependent gating in human HCN4 channel 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L. 登録日 2010-09-11 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the cAMP-dependent gating in the human HCN4 channel. J.Biol.Chem., 285, 2010
5BTX	Structure of the N-terminal domain of lpg1496 from Legionella pneumophila in complex with nucleotide 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, lpg1496 著者 Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2015-06-03 公開日 2015-08-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism. J.Biol.Chem., 290, 2015
6RSX	Regulatory Subunit of cAMP-dependant Protein Kinase A from Euglena gracilis at 1.6 A resolution 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Regulatory Subunit of Protein Kinase A (cAMP-dependent) from Euglena gracilis 著者 Volpato Santos, Y, Ober, V, Basquin, J, Boshart, M. 登録日 2019-05-22 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Regulatory Subunit of Protein Kinase A (cAMP-dependent) from Euglena gracilis at 1.6 A resolution To Be Published
5KBF	cAMP bound PfPKA-R (141-441) 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit, putative 著者 Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. 登録日 2016-06-03 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
6M63	Crystal structure of a cAMP sensor G-Flamp1. 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Chimera of Cyclic nucleotide-gated potassium channel mll3241 and Yellow fluorescent protein 著者 Zhou, Z, Chen, S, Wang, L, Chu, J. 登録日 2020-03-12 公開日 2021-09-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging. Nat Commun, 13, 2022
1Q5O	HCN2J 443-645 in the presence of cAMP, selenomethionine derivative 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E. 登録日 2003-08-08 公開日 2003-09-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 STRUCTURAL BASIS FOR MODULATION AND AGONIST SPECIFICITY OF HCN PACEMAKER CHANNELS Nature, 425, 2003
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. 登録日 2017-10-02 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of bacterial transcription activation. Science, 358, 2017
5K8S	cAMP bound PfPKA-R (297-441) 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit 著者 Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. 登録日 2016-05-31 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
3OF1	Crystal Structure of Bcy1, the Yeast Regulatory Subunit of PKA 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase regulatory subunit 著者 Rinaldi, J, Wu, J, Yang, J, Ralston, C.Y, Sankaran, B, Moreno, S, Taylor, S.S. 登録日 2010-08-13 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling. Structure, 18, 2010
3BPZ	HCN2-I 443-460 E502K in the presence of cAMP 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Craven, K.B, Olivier, N.B, Zagotta, W.N. 登録日 2007-12-19 公開日 2008-03-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 C-terminal movement during gating in cyclic nucleotide-modulated channels. J.Biol.Chem., 283, 2008
6UQF	Human HCN1 channel in a hyperpolarized conformation 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 著者 Lee, C.-H, MacKinnon, R. 登録日 2019-10-19 公開日 2019-12-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell, 179, 2019
3ETQ	X-ray structure of cysteine-free fragment of mHCN2 C-terminal region from amino acids 443-630 including C508N, C584S, and C601S mutations 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Flynn, G.E. 登録日 2008-10-08 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mapping the structure and conformational movements of proteins with transition metal ion FRET. Nat.Methods, 6, 2009
6UQG	Human HCN1 channel Y289D mutant 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 著者 Lee, C.-H, MacKinnon, R. 登録日 2019-10-19 公開日 2019-12-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell, 179, 2019
4D7T	Structure of the SthK Carboxy-Terminal Region in complex with cAMP 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, STHK_CNBD_CAMP 著者 Kesters, D, Brams, M, Nys, M, Wijckmans, E, Spurny, R, Voets, T, Tytgat, J, Ulens, C. 登録日 2014-11-27 公開日 2015-02-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.582 Å) 主引用文献 Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels. Plos One, 10, 2015
5J3U	Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Protein Kinase A 著者 El Bakkouri, M, Walker, J.R, Tempel, W, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, L, Structural Genomics Consortium (SGC) 登録日 2016-03-31 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP To Be Published
1Q43	HCN2I 443-640 in the presence of cAMP, selenomethionine derivative 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E. 登録日 2003-08-01 公開日 2003-09-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for modulation and agonist specificity of HCN pacemaker channels Nature, 425, 2003
3SHR	Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cGMP-dependent protein kinase 1 著者 Osborne, B.W, Wu, J, Taylor, S.S, Dostmann, W.R. 登録日 2011-06-16 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication. Structure, 19, 2011
5CIZ	E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*CP*AP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ... 著者 Napoli, A.A, Lawson, C.L. 登録日 2015-07-13 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (5.0098 Å) 主引用文献 The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element Biochemistry, 2020
2ZMF	Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 著者 Handa, N, Kishishita, S, Mizohata, E, Omori, K, Kotera, J, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-04-17 公開日 2008-04-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP J.Biol.Chem., 283, 2008
4HBN	Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L. 登録日 2012-09-28 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel. Structure, 20, 2012
6HQ5	Structure of EAL Enzyme Bd1971 - cAMP and cyclic-di-GMP bound form 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, ... 著者 Lovering, A.L, Cadby, I.T. 登録日 2018-09-24 公開日 2019-07-31 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase. Embo J., 38, 2019
5W10	Lcd1 GAF domain in complex with cAMP ligand 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cGMP-specific phosphodiesterase 著者 Guzzo, C.R, Maciel, N.K, Barbosa, A.S, Farah, C.S. 登録日 2017-06-01 公開日 2017-06-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species. J. Mol. Biol., 429, 2017

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