4TXZ
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP
Summary for 4TXZ
| Entry DOI | 10.2210/pdb4txz/pdb |
| Descriptor | Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (4 entities in total) |
| Functional Keywords | nucleotidyl transferase, cyclic nucleotide synthase, cgas, transferase |
| Biological source | Vibrio cholerae O1 biovar El Tor str. N16961 |
| Total number of polymer chains | 2 |
| Total formula weight | 95072.26 |
| Authors | Kranzusch, P.J.,Lee, A.S.Y.,Wilson, S.C.,Solovykh, M.S.,Vance, R.E.,Berger, J.M.,Doudna, J.A. (deposition date: 2014-07-07, release date: 2014-08-13, Last modification date: 2023-12-27) |
| Primary citation | Kranzusch, P.J.,Lee, A.S.,Wilson, S.C.,Solovykh, M.S.,Vance, R.E.,Berger, J.M.,Doudna, J.A. Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity. Cell, 158:1011-1021, 2014 Cited by PubMed: 25131990DOI: 10.1016/j.cell.2014.07.028 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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