5KJX

Co-crystal Structure of PKA RI alpha CNB-B domain with cAMP

Summary for 5KJX

Entry DOI	10.2210/pdb5kjx/pdb
Related	5KJY 5KJZ
Descriptor	cAMP-dependent protein kinase type I-alpha regulatory subunit, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
Functional Keywords	cyclic nucleotide, camp-dependent protein kinase, nucleotide selectivity, cyclic nucleotide binding domain, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	17285.71
Authors	Lorenz, R.,Moon, E.,Kim, J.J.,Huang, G.Y.,Kim, C.,Herberg, F.W. (deposition date: 2016-06-20, release date: 2017-06-28, Last modification date: 2023-09-27)
Primary citation	Lorenz, R.,Moon, E.W.,Kim, J.J.,Schmidt, S.H.,Sankaran, B.,Pavlidis, I.V.,Kim, C.,Herberg, F.W. Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474:2389-2403, 2017 Cited by PubMed: 28583991 DOI: 10.1042/BCJ20160969 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation