5KJZ
Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP
Summary for 5KJZ
Entry DOI | 10.2210/pdb5kjz/pdb |
Related | 5KJX 5KJY |
Descriptor | cAMP-dependent protein kinase type I-alpha regulatory subunit, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | cyclic nucleotide, camp-dependent protein kinase, nucleotide selectivity, cyclic nucleotide binding domain, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 17616.06 |
Authors | Lorenz, R.,Moon, E.,Kim, J.J.,Huang, G.Y.,Kim, C.,Herberg, F.W. (deposition date: 2016-06-20, release date: 2017-06-28, Last modification date: 2024-03-06) |
Primary citation | Lorenz, R.,Moon, E.W.,Kim, J.J.,Schmidt, S.H.,Sankaran, B.,Pavlidis, I.V.,Kim, C.,Herberg, F.W. Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474:2389-2403, 2017 Cited by PubMed: 28583991DOI: 10.1042/BCJ20160969 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.347 Å) |
Structure validation
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