4MKP

Crystal structure of human cGAS apo form

Summary for 4MKP

Entry DOI	10.2210/pdb4mkp/pdb
Descriptor	Cyclic GMP-AMP synthase, ZINC ION (3 entities in total)
Functional Keywords	nucleotidyltransferase, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytosol: Q8N884
Total number of polymer chains	1
Total formula weight	42614.45
Authors	Kato, K.,Ishii, R.,Ishitani, R.,Nureki, O. (deposition date: 2013-09-05, release date: 2013-10-30, Last modification date: 2023-11-08)
Primary citation	Kato, K.,Ishii, R.,Goto, E.,Ishitani, R.,Tokunaga, F.,Nureki, O. Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS Plos One, 8:e76983-e76983, 2013 Cited by PubMed: 24116191 DOI: 10.1371/journal.pone.0076983 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.953 Å)

Structure validation