6IHB
| Adeno-Associated Virus 2 in complex with AAVR | Descriptor: | Capsid protein VP1, Dyslexia-associated protein KIAA0319-like protein | Authors: | Lou, Z.Y, Zhang, R. | Deposit date: | 2018-09-29 | Release date: | 2019-03-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Adeno-associated virus 2 bound to its cellular receptor AAVR. Nat Microbiol, 4, 2019
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6IH9
| Adeno-Associated Virus 2 at 2.8 ang | Descriptor: | Capsid protein VP1 | Authors: | Lou, Z.Y, Zhang, R. | Deposit date: | 2018-09-29 | Release date: | 2019-07-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Adeno-associated virus 2 bound to its cellular receptor AAVR. Nat Microbiol, 4, 2019
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3ULZ
| Crystal structure of apo BAK1 | Descriptor: | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | Authors: | Lou, Z.Y, Yan, L.M, Ma, Y.Y. | Deposit date: | 2011-11-11 | Release date: | 2012-11-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for BAK1 activation To be Published
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3UIM
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3ULX
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3NGM
| Crystal structure of lipase from Gibberella zeae | Descriptor: | Extracellular lipase | Authors: | Lou, Z.Y, Li, M, Sun, Y.N, Liu, Y, Liu, Z, Rao, Z.H. | Deposit date: | 2010-06-12 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a secreted lipase from Gibberella zeae reveals a novel "double-lock" mechanism Protein Cell, 1, 2010
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7BWD
| Structure of Dot1L-H2BK34ub Nucleosome Complex | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Lou, Z.Y, Liu, L, Cao, L, Ai, H.S, Sun, Z.X. | Deposit date: | 2020-04-14 | Release date: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (4.32 Å) | Cite: | Structure of the Dot1L-H2BK34ub Nucleosome Complex Reveals an Unprecedented Crosstalk Activation Mechanism through Nucleosome Shape Distortion To Be Published
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6ADL
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6ADR
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6ADS
| Structure of Seneca Valley Virus in acidic conditions | Descriptor: | VP1, VP2, VP3, ... | Authors: | Lou, Z.Y, Cao, L. | Deposit date: | 2018-08-02 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1 Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6ADT
| Structure of Seneca Valley Virus in neutral condition | Descriptor: | VP1, VP2, VP3, ... | Authors: | Lou, Z.Y, Cao, L. | Deposit date: | 2018-08-02 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1 Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6ADM
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3S0Z
| Crystal structure of New Delhi Metallo-beta-lactamase (NDM-1) | Descriptor: | Metallo-beta-lactamase, ZINC ION | Authors: | Guo, Y, Wang, J, Niu, G.J, Shui, W.Q, Sun, Y.N, Lou, Z.Y, Rao, Z.H. | Deposit date: | 2011-05-13 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A structural view of the antibiotic degradation enzyme NDM-1 from a superbug. Protein Cell, 2011
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3MTV
| The Crystal Structure of the PRRSV Nonstructural Protein Nsp1 | Descriptor: | Papain-like cysteine protease | Authors: | Xue, F, Sun, Y.N, Yan, L.M, Zhao, C, Lou, Z.Y, Rao, Z.H. | Deposit date: | 2010-04-30 | Release date: | 2010-05-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease J.Virol., 84, 2010
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3WD5
| Crystal structure of TNFalpha in complex with Adalimumab Fab fragment | Descriptor: | Adalimumab Heavy Chain, Adalimumab Light Chain, Tumor necrosis factor | Authors: | Hu, S, Liang, S.Y, Guo, Y.J, Lou, Z.Y. | Deposit date: | 2013-06-06 | Release date: | 2013-08-14 | Last modified: | 2015-07-01 | Method: | X-RAY DIFFRACTION (3.101 Å) | Cite: | Comparison of the inhibition mechanisms of adalimumab and infliximab in treating tumor necrosis factor alpha-associated diseases from a molecular view J.Biol.Chem., 288, 2013
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7EIZ
| Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading | Descriptor: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | Authors: | Yan, L, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2021-04-01 | Release date: | 2021-09-22 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY | Cite: | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading Cell, 184, 2021
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4R3D
| Crystal structure of MERS Coronavirus papain like protease | Descriptor: | Non-structural protein 3, ZINC ION | Authors: | Kong, L.Y, Wang, Q, Ming, Z.H, Shaw, N, Sun, Y.N, Yan, L.M, Lou, Z.Y, Rao, Z.H. | Deposit date: | 2014-08-15 | Release date: | 2015-08-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.818 Å) | Cite: | The Crystal Structures of Middle East Respiratory Syndrome Coronavirus Papain-like Protease and Its Complex with an Inhibitor To be Published
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5GO3
| Crystal structure of a di-nucleotide cyclase Vibrio mutant | Descriptor: | Cyclic GMP-AMP synthase | Authors: | Ming, Z.H, Wang, W, Xie, Y.C, Chen, Y.C, Yan, L.M, Lou, Z.Y. | Deposit date: | 2016-07-26 | Release date: | 2016-11-02 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a di-nucleotide cyclase Vibrio mutant To Be Published
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4G3Y
| Crystal structure of TNF-alpha in complex with Infliximab Fab fragment | Descriptor: | Tumor necrosis factor, infliximab Fab H, infliximab Fab L | Authors: | Liang, S.Y, Dai, J.X, Guo, Y.J, Lou, Z.Y. | Deposit date: | 2012-07-15 | Release date: | 2013-03-27 | Last modified: | 2013-08-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for treating tumor necrosis factor alpha (TNFalpha)-associated diseases with the therapeutic antibody infliximab J.Biol.Chem., 288, 2013
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7EGQ
| Co-transcriptional capping machineries in SARS-CoV-2 RTC: Coupling of N7-methyltransferase and 3'-5' exoribonuclease with polymerase reveals mechanisms for capping and proofreading | Descriptor: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | Authors: | Yan, L.M, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2021-03-25 | Release date: | 2021-07-21 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading. Cell, 184, 2021
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7FAC
| Crystal Structure of C-terminus of the non-structural protein 2 from SARS coronavirus | Descriptor: | Non-structural protein 2, ZINC ION | Authors: | Li, Y.Y, Ren, Z.L, Bao, Z.H, Ming, Z.H, Yan, L.M, Lou, Z.Y, Rao, Z.H. | Deposit date: | 2021-07-06 | Release date: | 2022-08-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | The Life of SARS-CoV-2 Inside Cells: Replication-Transcription Complex Assembly and Function. Annu.Rev.Biochem., 91, 2022
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7FA1
| Crystal Structure of N-terminus of the non-structural protein 2 from SARS coronavirus | Descriptor: | Non-structural protein 2, ZINC ION | Authors: | Li, Y.Y, Ren, Z.L, Bao, Z.H, Ming, Z.H, Yan, L.M, Lou, Z.Y, Rao, Z.H. | Deposit date: | 2021-07-05 | Release date: | 2022-08-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Life of SARS-CoV-2 Inside Cells: Replication-Transcription Complex Assembly and Function. Annu.Rev.Biochem., 91, 2022
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8GWO
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-17 | Release date: | 2022-11-30 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWG
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-17 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWI
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-17 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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