4KRW
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3DC8
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3DYJ
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3DAD
| Crystal structure of the N-terminal regulatory domains of the formin FHOD1 | 分子名称: | FH1/FH2 domain-containing protein 1 | 著者 | Schulte, A, Stolp, B, Schonichen, A, Pylypenko, O, Rak, A, Fackler, O.T, Geyer, M. | 登録日 | 2008-05-29 | 公開日 | 2008-09-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Human Formin FHOD1 Contains a Bipartite Structure of FH3 and GTPase-Binding Domains Required for Activation. Structure, 16, 2008
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3DBZ
| human surfactant protein D | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Pulmonary surfactant-associated protein D | 著者 | Head, J.F. | 登録日 | 2008-06-02 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Interaction of recombinant surfactant protein D with lipopolysaccharide: conformation and orientation of bound protein by IRRAS and simulations. Biochemistry, 47, 2008
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4HNA
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4KC0
| mSTING | 分子名称: | Stimulator of interferon genes protein | 著者 | Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H. | 登録日 | 2013-04-24 | 公開日 | 2013-05-29 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING Acta Crystallogr.,Sect.D, 69, 2013
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3DDP
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3DKK
| Aged Form of Human Butyrylcholinesterase Inhibited by Tabun | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Nachon, F, Carletti, E. | 登録日 | 2008-06-25 | 公開日 | 2008-12-02 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation. J.Am.Chem.Soc., 130, 2008
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5XXU
| Small subunit of Toxoplasma gondii ribosome | 分子名称: | 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ... | 著者 | LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | 登録日 | 2017-07-05 | 公開日 | 2017-08-30 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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7LML
| Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid | 分子名称: | 6-iodanyl-1~{H}-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ... | 著者 | Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J. | 登録日 | 2021-02-05 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. Proteins, 89, 2021
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7XB5
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7XMA
| Crystal structure of Bovine heart cytochrome c oxidase, apo structure with DMSO | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | 著者 | Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Takashima, S, Shintani, Y. | 登録日 | 2022-04-25 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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7XMB
| Crystal structure of Bovine heart cytochrome c oxidase, the structure complexed with an allosteric inhibitor T113 | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | 著者 | Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Shintani, Y, Takashima, S. | 登録日 | 2022-04-25 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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7WZX
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | 分子名称: | (2~{S},4~{S},6~{R})-2-[(2~{S},3~{R},5~{S},6~{R})-3,5-bis(methylamino)-2,4,6-tris(oxidanyl)cyclohexyl]oxy-6-methyl-4-oxidanyl-oxan-3-one, 4Fe-4S cluster-binding domain-containing protein, GLYCEROL, ... | 著者 | Hou, X.L, Zhou, J.H. | 登録日 | 2022-02-19 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.980013 Å) | 主引用文献 | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7WZV
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | 分子名称: | (1~{S},2~{R},4~{S},5~{R})-2,4-bis(methylamino)-6-[(2~{S},3~{R},4~{S},6~{R})-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-cyclohexane-1,3,5-triol, 1,2-ETHANEDIOL, 4Fe-4S cluster-binding domain-containing protein, ... | 著者 | Zhou, J.H, Hou, X.L. | 登録日 | 2022-02-19 | 公開日 | 2022-12-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.899313 Å) | 主引用文献 | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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7X0B
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | 分子名称: | 4Fe-4S cluster-binding domain-containing protein, CHLORIDE ION, GLYCEROL, ... | 著者 | Hou, X.L, Zhou, J.H. | 登録日 | 2022-02-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.02027535 Å) | 主引用文献 | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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5FFO
| Integrin alpha V beta 6 in complex with pro-TGF-beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Dong, X, Zhao, B, Springer, T.A. | 登録日 | 2015-12-18 | 公開日 | 2017-01-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Force interacts with macromolecular structure in activation of TGF-beta. Nature, 542, 2017
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7XMW
| Crystal structure of anti-CRISPR protein AcrVIA2 | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, AcrVIA2, SELENIUM ATOM, ... | 著者 | Yan, X, Li, X, Song, G. | 登録日 | 2022-04-27 | 公開日 | 2023-05-31 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structure of AcrVIA2 and its binding mechanism to CRISPR-Cas13a. Biochem.Biophys.Res.Commun., 612, 2022
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4YH8
| Structure of yeast U2AF complex | 分子名称: | Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ZINC ION | 著者 | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | 登録日 | 2015-02-27 | 公開日 | 2015-08-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit. Genes Dev., 29, 2015
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6ESG
| Nucleosome breathing : Class 2 | 分子名称: | DNA (141-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Bilokapic, S, Halic, M. | 登録日 | 2017-10-20 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
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7LTN
| Crystal structure of Mpro in complex with inhibitor CDD-1713 | 分子名称: | 2-[4-(1~{H}-indazol-4-yl)-2-methanoyl-6-methoxy-phenoxy]-~{N},~{N}-dimethyl-ethanamide, 3C-like proteinase | 著者 | Lu, S, Palzkill, T, Matzuk, M, Young, D, Melek, N, Chamakuri, S. | 登録日 | 2021-02-19 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M pro inhibitors. Proc.Natl.Acad.Sci.USA, 118, 2021
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6ESH
| Nucleosome breathing : Class 3 | 分子名称: | DNA (137-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Bilokapic, S, Halic, M. | 登録日 | 2017-10-20 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
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6ESI
| Nucleosome breathing : Class 4 | 分子名称: | DNA (133-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Bilokapic, S, Halic, M. | 登録日 | 2017-10-20 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
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7W0E
| dmDicer2-LoqsPD-dsRNA Active-dicing status | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | 登録日 | 2021-11-18 | 公開日 | 2022-04-27 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD. Nature, 607, 2022
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