4HNA

Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN

Summary for 4HNA

DescriptorTubulin alpha chain, Tubulin beta chain, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D2, ... (10 entities in total)
Functional Keywordsalpha-tubulin, beta-tubulin, darpin, gtpase, kinesin, microtubule, tubulin, motor protein
Biological sourceARTIFICIAL GENE
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Cellular locationCytoplasm, cytoskeleton  D0VWZ0 D0VWY9 P33176
Total number of polymer chains4
Total molecular weight159175.07
Authors
Gigant, B.,Knossow, M. (deposition date: 2012-10-19, release date: 2013-06-12, Last modification date: 2017-11-15)
Primary citation
Gigant, B.,Wang, W.,Dreier, B.,Jiang, Q.,Pecqueur, L.,Pluckthun, A.,Wang, C.,Knossow, M.
Structure of a kinesin-tubulin complex and implications for kinesin motility.
Nat.Struct.Mol.Biol., 20:1001-1007, 2013
PubMed: 23872990 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.2624
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.19 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22551.2%6.0%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution