4HNA

Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tubulin alpha chain	polymer	451	50204.4	1	UniProt (D0VWZ0) Pfam (PF00091) Pfam (PF03953) In PDB	Ovis aries (domestic sheep lambs wild sheep)
2	B	Tubulin beta chain	polymer	445	49983.8	1	UniProt (D0VWY9) Pfam (PF00091) Pfam (PF03953) In PDB	Ovis aries (domestic sheep lambs wild sheep)
3	D	DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D2	polymer	169	18140.3	1		ARTIFICIAL GENE
4	K	Kinesin-1 heavy chain	polymer	349	39174.0	1	UniProt (P33176) Pfam (PF00225) In PDB	Homo sapiens (human)	Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC
5	A	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
6	A, B, K	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
7	B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
8	B, K	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF)
9	K	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
10		water	water		18.0	2	Chemie (HOH)

Sequence modifications

A: 1 - 451 (UniProt: D0VWZ0)

PDB	External Database	Details
Ser 232	Gly 232	SEE REMARK 999
Ser 340	Thr 340	SEE REMARK 999

B: 1 - 455 (UniProt: D0VWY9)

PDB	External Database	Details
Ile 318	Val 316	SEE REMARK 999

K: 1 - 349 (UniProt: P33176)

PDB	External Database	Details
Ser 7	Cys 7	SEE REMARK 999
Ala 65	Cys 65	SEE REMARK 999
Ala 168	Cys 168	SEE REMARK 999
Ser 174	Cys 174	SEE REMARK 999
Ala 294	Cys 294	SEE REMARK 999
Ser 330	Cys 330	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	157502.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1672.4
All*	Total formula weight	159175.1

*Water molecules are not included.