7LML
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid
Summary for 7LML
Entry DOI | 10.2210/pdb7lml/pdb |
Related | 6XQ1 6XQ3 6XQ5 6XQ6 6XQ7 6XQ8 6XQ9 |
Descriptor | Advanced glycosylation end product-specific receptor, ACETATE ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | rage, ig-like domain, receptor, advanced glycation end products, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 48984.59 |
Authors | Salay, L.E.,Kozlyuk, N.,Gilston, B.A.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. (deposition date: 2021-02-05, release date: 2021-12-15, Last modification date: 2023-10-18) |
Primary citation | Kozlyuk, N.,Gilston, B.A.,Salay, L.E.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. Proteins, 89:1399-1412, 2021 Cited by PubMed: 34156100DOI: 10.1002/prot.26162 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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