Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 52 results
7VOC
DownloadVisualize
BU of 7voc by Molmil
The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S
Descriptor: (2~{S},3~{S},4~{S},5~{R},6~{R})-6-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Cytosylglucuronate decarboxylase, GLYCEROL, ...
Authors:Hou, X.L, Zhou, J.H.
Deposit date:2021-10-13
Release date:2022-05-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.62005424 Å)
Cite:Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
J.Am.Chem.Soc., 144, 2022
7VOB
DownloadVisualize
BU of 7vob by Molmil
The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S
Descriptor: CHLORIDE ION, Cytosylglucuronate decarboxylase, GLYCEROL, ...
Authors:Hou, X.L, Zhou, J.H.
Deposit date:2021-10-13
Release date:2022-05-04
Method:X-RAY DIFFRACTION (2.092241 Å)
Cite:Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
J.Am.Chem.Soc., 144, 2022
7WZX
DownloadVisualize
BU of 7wzx by Molmil
The structure of a Twitch Radical SAM Dehydrogenase SpeY
Descriptor: (2~{S},4~{S},6~{R})-2-[(2~{S},3~{R},5~{S},6~{R})-3,5-bis(methylamino)-2,4,6-tris(oxidanyl)cyclohexyl]oxy-6-methyl-4-oxidanyl-oxan-3-one, 4Fe-4S cluster-binding domain-containing protein, GLYCEROL, ...
Authors:Hou, X.L, Zhou, J.H.
Deposit date:2022-02-19
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.980013 Å)
Cite:Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase.
J.Am.Chem.Soc., 144, 2022
7X0B
DownloadVisualize
BU of 7x0b by Molmil
The structure of a Twitch Radical SAM Dehydrogenase SpeY
Descriptor: 4Fe-4S cluster-binding domain-containing protein, CHLORIDE ION, GLYCEROL, ...
Authors:Hou, X.L, Zhou, J.H.
Deposit date:2022-02-21
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.02027535 Å)
Cite:Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase.
J.Am.Chem.Soc., 144, 2022
7XAX
DownloadVisualize
BU of 7xax by Molmil
Crystal structure of SARS coronavirus main protease in complex with Baicalei
Descriptor: 3C-like proteinase nsp5, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
Authors:Zhou, X.L, Li, J, Zhang, J.
Deposit date:2022-03-19
Release date:2023-03-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of SARS coronavirus main protease in complex with Baicalei
To Be Published
8J36
DownloadVisualize
BU of 8j36 by Molmil
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF00835231
To Be Published
7VBF
DownloadVisualize
BU of 7vbf by Molmil
1.3 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 8.5
Descriptor: Nucleoprotein
Authors:Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-08-31
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:1.3 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 8.5
To Be Published
7VBE
DownloadVisualize
BU of 7vbe by Molmil
1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0
Descriptor: Nucleoprotein
Authors:Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-08-31
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0
To Be Published
7C2Y
DownloadVisualize
BU of 7c2y by Molmil
The crystal structure of COVID-2019 main protease in the apo state
Descriptor: 3C-like proteinase
Authors:Zhou, X.L, Zhong, F.L, Lin, C, Zhou, H, Hu, X.H, Wang, Q.S, Li, J, Zhang, J.
Deposit date:2020-05-10
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:COVID-2019 main protease in the apo state
To Be Published
7F42
DownloadVisualize
BU of 7f42 by Molmil
PARP15 catalytic domain in complex with Iniparib
Descriptor: 4-iodo-3-nitrobenzamide, Protein mono-ADP-ribosyltransferase PARP15
Authors:Zhou, X.L, Zhou, H, Li, J, Zhang, J.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:PARP15 catalytic domain in complex with Iniparib
To Be Published
7F43
DownloadVisualize
BU of 7f43 by Molmil
PARP15 catalytic domain in complex with Niraparib
Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, Protein mono-ADP-ribosyltransferase PARP15
Authors:Zhou, X.L, Zhou, H, Li, J, Zhang, J.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:PARP15 catalytic domain in complex with Niraparib
To Be Published
7F41
DownloadVisualize
BU of 7f41 by Molmil
PARP15 catalytic domain in complex with 3-AMINOBENZAMIDE
Descriptor: 3-aminobenzamide, Protein mono-ADP-ribosyltransferase PARP15
Authors:Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39721382 Å)
Cite:PARP15 catalytic domain in complex with 3-AMINOBENZAMIDE
To Be Published
7VVP
DownloadVisualize
BU of 7vvp by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with PF07304814
Descriptor: 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate
Authors:Zhou, X.L, Zhong, F.L, Lin, C, Zeng, P, Zhang, J, Li, J.
Deposit date:2021-11-07
Release date:2022-08-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814
J.Mol.Biol., 434, 2022
7VLQ
DownloadVisualize
BU of 7vlq by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with PF07321332 in spacegroup P212121
Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase
Authors:Zhou, X.L, Zhong, F.L, Lin, C, Zhang, J, Li, J.
Deposit date:2021-10-05
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.939106 Å)
Cite:Structural Basis of the Main Proteases of Coronavirus Bound to Drug Candidate PF-07321332.
J.Virol., 96, 2022
7VLP
DownloadVisualize
BU of 7vlp by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with PF07321332 in spacegroup P1211
Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, Replicase polyprotein 1a
Authors:Zhou, X.L, Zhong, F.L, Lin, C, Li, J, Zhang, J.
Deposit date:2021-10-05
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.50251937 Å)
Cite:Structural Basis of the Main Proteases of Coronavirus Bound to Drug Candidate PF-07321332.
J.Virol., 96, 2022
7XRS
DownloadVisualize
BU of 7xrs by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with inhibitor YH-53
Descriptor: N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, Replicase polyprotein 1a
Authors:Zhou, X.L, Zhong, F.L, Lin, C, Zeng, P, Zhang, J, Li, J.
Deposit date:2022-05-11
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor.
Viruses, 14, 2022
8HQJ
DownloadVisualize
BU of 8hqj by Molmil
Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with inhibitor YH-53
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Zhang, J, Li, J.
Deposit date:2022-12-13
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with inhibitor YH-53
To Be Published
8J37
DownloadVisualize
BU of 8j37 by Molmil
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with PF00835231
To Be Published
8J35
DownloadVisualize
BU of 8j35 by Molmil
Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF00835231
To Be Published
8J3A
DownloadVisualize
BU of 8j3a by Molmil
Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with PF00835231
To Be Published
8J32
DownloadVisualize
BU of 8j32 by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of SARS-Cov-2 main protease in complex with PF00835231
To Be Published
8J38
DownloadVisualize
BU of 8j38 by Molmil
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF00835231
To Be Published
8J34
DownloadVisualize
BU of 8j34 by Molmil
Crystal structure of MERS main protease in complex with PF00835231
Descriptor: N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, ORF1a
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of MERS main protease in complex with PF00835231
To Be Published
8J3B
DownloadVisualize
BU of 8j3b by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF00835231
To Be Published
8J39
DownloadVisualize
BU of 8j39 by Molmil
Crystal structure of SARS-Cov-2 main protease V186F mutant in complex with PF00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-04-16
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Crystal structure of SARS-Cov-2 main protease V186F mutant in complex with PF00835231
To Be Published

 

123>

219140

PDB entries from 2024-05-01

PDB statisticsPDBj update infoContact PDBjnumon