8J3B

Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF00835231

Summary for 8J3B

• Entry DOI: 10.2210/pdb8j3b/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 67366.95

Authors

Zhou, X.L.,Lin, C.,Zou, X.F.,Zhang, J.,Li, J. (deposition date: 2023-04-16, release date: 2024-04-17, Last modification date: 2024-11-13)

• Primary citation: Zhou, X.L.,Lin, C.,Zou, X.F.,Zhang, J.,Li, J.; Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF00835231; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)