7VOC

The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S

Summary for 7VOC

Entry DOI	10.2210/pdb7voc/pdb
Descriptor	Cytosylglucuronate decarboxylase, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (6 entities in total)
Functional Keywords	radical sam enzyme, dehydratase, blasticidin s, enzyme catalysis
Biological source	Streptomyces griseochromogenes
Total number of polymer chains	1
Total formula weight	41810.46
Authors	Hou, X.L.,Zhou, J.H. (deposition date: 2021-10-13, release date: 2022-05-04, Last modification date: 2023-11-29)
Primary citation	Lee, Y.H.,Hou, X.,Chen, R.,Feng, J.,Liu, X.,Ruszczycky, M.W.,Gao, J.M.,Wang, B.,Zhou, J.,Liu, H.W. Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. J.Am.Chem.Soc., 144:4478-4486, 2022 Cited by PubMed: 35238201 DOI: 10.1021/jacs.1c12010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.62005420008 Å)

Structure validation