7X0B
The structure of a Twitch Radical SAM Dehydrogenase SpeY
Summary for 7X0B
Entry DOI | 10.2210/pdb7x0b/pdb |
Descriptor | 4Fe-4S cluster-binding domain-containing protein, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (8 entities in total) |
Functional Keywords | spectinomycin, twitch radical sam dehydrogenase, epimerase, biosynthetic protein |
Biological source | Streptomyces spectabilis |
Total number of polymer chains | 2 |
Total formula weight | 75397.29 |
Authors | Hou, X.L.,Zhou, J.H. (deposition date: 2022-02-21, release date: 2022-12-28, Last modification date: 2023-11-29) |
Primary citation | Zhang, J.,Hou, X.,Chen, Z.,Ko, Y.,Ruszczycky, M.W.,Chen, Y.,Zhou, J.,Liu, H.W. Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144:9910-9919, 2022 Cited by PubMed: 35622017DOI: 10.1021/jacs.2c02676 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02027524648 Å) |
Structure validation
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