7F43
PARP15 catalytic domain in complex with Niraparib
Summary for 7F43
| Entry DOI | 10.2210/pdb7f43/pdb |
| Descriptor | Protein mono-ADP-ribosyltransferase PARP15, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (3 entities in total) |
| Functional Keywords | glycosyltransferase, transferase, mono-adp-ribosyltransferase 15 |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 46372.00 |
| Authors | Zhou, X.L.,Zhou, H.,Li, J.,Zhang, J. (deposition date: 2021-06-17, release date: 2022-06-22, Last modification date: 2025-03-26) |
| Primary citation | Zhou, X.,Yang, Y.,Xu, Q.,Zhou, H.,Zhong, F.,Deng, J.,Zhang, J.,Li, J. Crystal structures of the catalytic domain of human PARP15 in complex with small molecule inhibitors Biochem.Biophys.Res.Commun., 622:93-100, 2022 Cited by DOI: 10.1016/j.bbrc.2022.06.070PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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