8X7T
| MCM in the Apo state. | Descriptor: | mini-chromosome maintenance complex 3 | Authors: | Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Gilbert, R.J.C, Zhang, P. | Deposit date: | 2023-11-25 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | MCM in the Apo state To Be Published
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8X7U
| MCM in complex with dsDNA in presence of ATP. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mini-chromosome maintenance complex 3 | Authors: | Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Gilbert, R.J.C, Zhang, P. | Deposit date: | 2023-11-25 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | MCM in complex with dsDNA in presence of ATP To Be Published
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1O5W
| The structure basis of specific recognitions for substrates and inhibitors of rat monoamine oxidase A | Descriptor: | Amine oxidase [flavin-containing] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE | Authors: | Ma, J, Yoshimura, M, Yamashita, E, Nakagawa, A, Ito, A, Tsukihara, T. | Deposit date: | 2003-10-06 | Release date: | 2004-04-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of rat monoamine oxidase a and its specific recognitions for substrates and inhibitors. J.Mol.Biol., 338, 2004
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6UZ1
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6CSE
| Crystal structure of sodium/alanine symporter AgcS with L-alanine bound | Descriptor: | ALANINE, Monoclonal antibody FAB heavy chain, Monoclonal antibody FAB light chain, ... | Authors: | Ma, J, Reyes, F.E, Gonen, T. | Deposit date: | 2018-03-20 | Release date: | 2019-01-30 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6CSF
| Crystal structure of sodium/alanine symporter AgcS with D-alanine bound | Descriptor: | D-ALANINE, Monoclonal antibody FAB heavy chain, Monoclonal antibody FAB light chain, ... | Authors: | Ma, J, Reyes, F.E, Gonen, T. | Deposit date: | 2018-03-20 | Release date: | 2019-01-30 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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2LR1
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7RRG
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7EKA
| crystal structure of epigallocatechin binding with alpha-lactalbumin | Descriptor: | 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL, Alpha-lactalbumin | Authors: | Ma, J, Yao, Q, Chen, X, Zang, J. | Deposit date: | 2021-04-05 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Weak Binding of Epigallocatechin to alpha-Lactalbumin Greatly Improves Its Stability and Uptake by Caco-2 Cells. J.Agric.Food Chem., 69, 2021
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3MIL
| Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae | Descriptor: | GLYCEROL, Isoamyl acetate-hydrolyzing esterase | Authors: | Ma, J, Lu, Q, Yuan, Y, Li, K, Ge, H, Go, Y, Niu, L, Teng, M. | Deposit date: | 2010-04-11 | Release date: | 2010-11-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae reveals a novel active site architecture and the basis of substrate specificity Proteins, 79, 2011
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3T4H
| Crystal Structure of AlkB in complex with Fe(III) and N-Oxalyl-S-(3-nitrobenzyl)-L-cysteine | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, FE (III) ION, ... | Authors: | Ma, J, Aik, W.S, McDonough, M.A, Schofield, C.J. | Deposit date: | 2011-07-26 | Release date: | 2012-03-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic Acid demethylase. J.Med.Chem., 55, 2012
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3U4S
| Histone Lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to N-oxalyl-D-cysteine | Descriptor: | HISTONE 3 TAIL ANALOG (T11C Peptide), Lysine-specific demethylase 4A, N-(carboxycarbonyl)-D-cysteine, ... | Authors: | Ma, J, McDonough, M.A, Schofield, C.J. | Deposit date: | 2011-10-10 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases. Angew.Chem.Int.Ed.Engl., 51, 2012
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7VH3
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6AKM
| Crystal structure of SLMAP-SIKE1 complex | Descriptor: | GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1 | Authors: | Ma, J, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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7EXM
| The N-terminal crystal structure of SARS-CoV-2 NSP2 | Descriptor: | GLYCEROL, Non-structural protein 2, ZINC ION | Authors: | Ma, J, Chen, Z. | Deposit date: | 2021-05-27 | Release date: | 2021-06-16 | Last modified: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structure and Function of N-Terminal Zinc Finger Domain of SARS-CoV-2 NSP2. Virol Sin, 36, 2021
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7L1C
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7L1B
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7L1D
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4ZWJ
| Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser | Descriptor: | Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin | Authors: | Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR) | Deposit date: | 2015-05-19 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.302 Å) | Cite: | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature, 523, 2015
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1ZQ3
| NMR Solution Structure of the Bicoid Homeodomain Bound to the Consensus DNA Binding Site TAATCC | Descriptor: | 5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3', 5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3', Homeotic bicoid protein | Authors: | Baird-Titus, J.M, Rance, M, Clark-Baldwin, K, Ma, J, Vrushank, D. | Deposit date: | 2005-05-18 | Release date: | 2006-02-14 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site. J.Mol.Biol., 356, 2006
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8HF0
| DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state | Descriptor: | Dicer-2, isoform A, LD06392p, ... | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | Deposit date: | 2022-11-09 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
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8HF1
| DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state | Descriptor: | Dicer-2, isoform A, LD06392p, ... | Authors: | Su, S, Wang, J, Ma, J. | Deposit date: | 2022-11-09 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
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6X9H
| Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1) | Descriptor: | 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Liu, Y, Ma, J, DesJarlais, R.L, Hagan, R, Rech, J, Lin, D, Liu, C, Miller, R, Schoellerman, J, Luo, J, Letavic, M, Grasberger, B, Maher, M. | Deposit date: | 2020-06-02 | Release date: | 2020-12-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1. Commun Biol, 4, 2021
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6Y8K
| Crystal structure of CD137 in complex with the cyclic peptide BCY10916 | Descriptor: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Upadhyaya, P, Kublin, J, Dods, R, Kristensson, J, Lahdenranta, J, Kleyman, M, Repash, E, Ma, J, Mudd, G, Van Rietschoten, K, Haines, E, Harrison, H, Beswick, P, Chen, L, McDonnell, K, Battula, S, Hurov, K, Keen, N. | Deposit date: | 2020-03-05 | Release date: | 2021-02-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.011 Å) | Cite: | Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist. J Immunother Cancer, 9, 2021
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4R4Z
| Structure of PNGF-II in P21 space group | Descriptor: | PNGF-II | Authors: | Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L. | Deposit date: | 2014-08-20 | Release date: | 2015-01-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Identification and
Characterization of a Novel Prokaryotic Peptide: N-glycosidase from
Elizabethkingia meningoseptica J.Biol.Chem., 2015
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