6UZ1

Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with Tax/HLA-A2

Summary for 6UZ1

• Entry DOI: 10.2210/pdb6uz1/pdb
• Descriptor: MHC class I antigen, A-2 alpha chain, Beta-2-microglobulin, LEU-LEU-PHE-GLY-TYR-PRO-VAL-TYR-VAL, ... (7 entities in total)
• Functional Keywords: single-chain t cell receptor, peptide major histocompatibility complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 139082.73

Authors

Ma, J.,Singh, N.K. (deposition date: 2019-11-14, release date: 2020-10-28, Last modification date: 2023-10-11)

• Primary citation: Singh, N.K.,Alonso, J.A.,Harris, D.T.,Anderson, S.D.,Ma, J.,Hellman, L.M.,Rosenberg, A.M.,Kolawole, E.M.,Evavold, B.D.,Kranz, D.M.,Baker, B.M.; An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.; Biochemistry, 59:4163-4175, 2020; PubMed: 33074657; DOI: 10.1021/acs.biochem.0c00689

Experimental method

X-RAY DIFFRACTION (3.14 Å)