6UZ1
Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with Tax/HLA-A2
Summary for 6UZ1
Entry DOI | 10.2210/pdb6uz1/pdb |
Descriptor | MHC class I antigen, A-2 alpha chain, Beta-2-microglobulin, LEU-LEU-PHE-GLY-TYR-PRO-VAL-TYR-VAL, ... (7 entities in total) |
Functional Keywords | single-chain t cell receptor, peptide major histocompatibility complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 139082.73 |
Authors | Ma, J.,Singh, N.K. (deposition date: 2019-11-14, release date: 2020-10-28, Last modification date: 2023-10-11) |
Primary citation | Singh, N.K.,Alonso, J.A.,Harris, D.T.,Anderson, S.D.,Ma, J.,Hellman, L.M.,Rosenberg, A.M.,Kolawole, E.M.,Evavold, B.D.,Kranz, D.M.,Baker, B.M. An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes. Biochemistry, 59:4163-4175, 2020 Cited by PubMed: 33074657DOI: 10.1021/acs.biochem.0c00689 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.14 Å) |
Structure validation
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