7WZV

The structure of a Twitch Radical SAM Dehydrogenase SpeY

Summary for 7WZV

• Entry DOI: 10.2210/pdb7wzv/pdb
• Descriptor: 4Fe-4S cluster-binding domain-containing protein, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (10 entities in total)
• Functional Keywords: twitch radical sam dehydrogenase; spectinomycin; x-ray crystallography, biosynthetic protein
• Biological source: Streptomyces spectabilis
• Total number of polymer chains: 2
• Total formula weight: 76803.42

Authors

Zhou, J.H.,Hou, X.L. (deposition date: 2022-02-19, release date: 2022-12-28)

• Primary citation: Zhang, J.,Hou, X.,Chen, Z.,Ko, Y.,Ruszczycky, M.W.,Chen, Y.,Zhou, J.,Liu, H.W.; Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase.; J.Am.Chem.Soc., 144:9910-9919, 2022; PubMed: 35622017; DOI: 10.1021/jacs.2c02676

Experimental method

X-RAY DIFFRACTION (1.89931293521 Å)