2DSR
 
 | | Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins | | 分子名称: | Insulin-like growth factor IB, Insulin-like growth factor-binding protein 4 | | 著者 | Sitar, T, Popowicz, G.M, Siwanowicz, I, Huber, R, Holak, T.A. | | 登録日 | 2006-07-05 | | 公開日 | 2006-08-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2EFA
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2G4M
 | | Insulin collected at 2.0 A wavelength | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G54
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2G56
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2GF1
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2H67
 | | NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Hua, Q.X, Liu, M, Hu, S.Q, Jia, W, Arvan, P, Weiss, M.A. | | 登録日 | 2006-05-30 | | 公開日 | 2006-07-18 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin: Structure and function of an Alab5 analog.
J.Biol.Chem., 281, 2006
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2HH4
 | | NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures | | 分子名称: | insulin A chain, insulin B chain | | 著者 | Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A. | | 登録日 | 2006-06-27 | | 公開日 | 2006-07-18 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain.
J.Biol.Chem., 281, 2006
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2HHO
 | | NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A. | | 登録日 | 2006-06-28 | | 公開日 | 2006-07-18 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain.
J.Biol.Chem., 281, 2006
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2HIU
 | | NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES | | 分子名称: | INSULIN | | 著者 | Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. | | 登録日 | 1996-10-08 | | 公開日 | 1997-04-01 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a protein in a kinetic trap.
Nat.Struct.Biol., 2, 1995
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2INS
 | | THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN | | 分子名称: | DES-PHE B1 INSULIN (CHAIN A), DES-PHE B1 INSULIN (CHAIN B), ZINC ION | | 著者 | Smith, G.D, Duax, W.L, Dodson, E.J, Dodson, G.G, Degraaf, R.A.G, Reynolds, C.D. | | 登録日 | 1982-05-10 | | 公開日 | 1982-08-05 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Structure of Des-Phe B1 Bovine Insulin
Acta Crystallogr.,Sect.B, 38, 1982
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2JMN
 | | NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2006-11-21 | | 公開日 | 2006-12-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264, 1996
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2JUM
 | | ThrA3-DKP-insulin | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2007-08-31 | | 公開日 | 2007-10-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.
J.Biol.Chem., 282, 2007
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2JUU
 | | allo-ThrA3 DKP-insulin | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2007-09-03 | | 公開日 | 2007-10-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.
J.Biol.Chem., 282, 2007
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2JUV
 | | AbaA3-DKP-insulin | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2007-09-05 | | 公開日 | 2007-10-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.
J.Biol.Chem., 282, 2007
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2JV1
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2JZQ
 | | Design of an Active Ultra-Stable Single-Chain Insulin Analog 20 Structures | | 分子名称: | Insulin | | 著者 | Hua, Q.X, Nakarawa, S, Jia, W.H, Huang, K, Philips, N.F, Hu, S.Q, Weiss, M.A. | | 登録日 | 2008-01-11 | | 公開日 | 2008-02-26 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications.
J.Biol.Chem., 283, 2008
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2K91
 | | Enhancing the activity of insulin by stereospecific unfolding | | 分子名称: | Insulin | | 著者 | Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2008-09-29 | | 公開日 | 2008-11-18 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009
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2K9R
 | | Enhancing the activity of insulin by stereospecific unfolding | | 分子名称: | Insulin | | 著者 | Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2008-10-23 | | 公開日 | 2008-11-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009
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2KJJ
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2KJU
 | | NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures | | 分子名称: | Insulin | | 著者 | Hua, Q.X, Huang, K, Hu, S.Q, Katsoyanni, P, Weiss, M.A. | | 登録日 | 2009-06-10 | | 公開日 | 2010-06-16 | | 最終更新日 | 2021-10-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Acceleration of Protein Fibrillation by Chiral Destabilization of Beta-Turn
To be Published
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2KQP
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2KQQ
 | | NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Hua, Q.X, Wan, Z.L, Zhao, M, Jia, W, Huang, K, Weiss, M.A. | | 登録日 | 2009-11-13 | | 公開日 | 2010-11-24 | | 最終更新日 | 2021-10-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Dynamics of an Turn-Stabilize But Ina Insulin Analog.
To be Published
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2KXK
 | | Human Insulin Mutant A22Gly-B31Lys-B32Arg | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Bocian, W, Kozerski, L. | | 登録日 | 2010-05-07 | | 公開日 | 2011-06-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Novel recombinant insulin analogue with flexible C - terminus in B chain. NMR structure of biosynthetic engineered A22G-B31K-B32R human insulin monomer in water /acetonitrile solution.
To be Published
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2L1Y
 | | NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A. | | 登録日 | 2010-08-09 | | 公開日 | 2011-08-31 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chiral Protein Engineering and its Application in G Health
To be Published
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