NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures

Summary for 2KQQ

DescriptorInsulin B chain, Insulin A chain (2 entities in total)
Functional Keywordshormone, human insulin, mutant, d-alanine substitution, protein stability, dynamics
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5808.62
Hua, Q.X.,Wan, Z.L.,Zhao, M.,Jia, W.,Huang, K.,Weiss, M.A. (deposition date: 2009-11-13, release date: 2010-11-24, Last modification date: 2011-07-13)
Primary citation
Hua, Q.X.,Wan, Z.L.,Zhao, M.,Jia, W.,Huang, K.,Weis, M.A.
Structure and Dynamics of an Turn-Stabilize But Ina Insulin Analog.
To be Published,
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers713.2%33.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report