2KQQ

NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures

Summary for 2KQQ

DescriptorInsulin B chain, Insulin A chain (2 entities in total)
Functional Keywordshormone, human insulin, mutant, d-alanine substitution, protein stability, dynamics
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5808.62
Authors
Hua, Q.X.,Wan, Z.L.,Zhao, M.,Jia, W.,Huang, K.,Weiss, M.A. (deposition date: 2009-11-13, release date: 2010-11-24, Last modification date: 2011-07-13)
Primary citation
Hua, Q.X.,Wan, Z.L.,Zhao, M.,Jia, W.,Huang, K.,Weis, M.A.
Structure and Dynamics of an Turn-Stabilize But Ina Insulin Analog.
To be Published,
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers713.2%33.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report