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2JMN

NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures

Replaces:  1LNPReplaces:  1VKS
Summary for 2JMN
Entry DOI10.2210/pdb2jmn/pdb
Related2H67
DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordshormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight5794.59
Authors
Hua, Q.X.,Hu, S.Q.,Frank, B.H.,Jia, W.H.,Chu, Y.C.,Wang, S.H.,Burke, G.T.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2006-11-21, release date: 2006-12-05, Last modification date: 2023-12-20)
Primary citationHua, Q.X.,Hu, S.Q.,Frank, B.H.,Jia, W.,Chu, Y.C.,Wang, S.H.,Burke, G.T.,Katsoyannis, P.G.,Weiss, M.A.
Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264:390-403, 1996
Cited by
PubMed: 8951384
DOI: 10.1006/jmbi.1996.0648
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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