Dynamics of insulin probed by 1H-NMR amide proton exchange anomalous flexibility of the receptor-binding surface

Summary for 2KJJ

DescriptorInsulin (2 entities in total)
Functional Keywordshormone, insulin, mutant, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, pharmaceutical, secreted
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5817.65
Hua, Q.X.,Weiss, M.A. (deposition date: 2009-05-29, release date: 2010-06-16, Last modification date: 2011-07-13)
Primary citation
Hua, Q.X.,Weiss, M.A.
Dynamics of Insulin Probed by 1H-NMR Amide Proton E Anomalous Flexibility of the Receptor-Binding Surfa
To be Published,
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers1212.7%22.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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