2G56

crystal structure of human insulin-degrading enzyme in complex with insulin B chain

Summary for 2G56

• Entry DOI: 10.2210/pdb2g56/pdb
• Related: 2G47 2G48 2G49 2G54
• Descriptor: Insulin-degrading enzyme, Insulin, 1,4-DIETHYLENE DIOXIDE, ... (4 entities in total)
• Functional Keywords: protein-peptide complex, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308
• Total number of polymer chains: 4
• Total formula weight: 236386.29

Authors

Shen, Y.,Tang, W.-J. (deposition date: 2006-02-22, release date: 2006-10-24, Last modification date: 2023-08-30)

• Primary citation: Shen, Y.,Joachimiak, A.,Rosner, M.R.,Tang, W.J.; Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.; Nature, 443:870-874, 2006; PubMed: 17051221; DOI: 10.1038/nature05143

Experimental method

X-RAY DIFFRACTION (2.2 Å)