2KXK

Human Insulin Mutant A22Gly-B31Lys-B32Arg

Summary for 2KXK

DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordshuman insulin, mutant, water/acetonitrile solution, hormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight6161.08
Authors
Bocian, W.,Kozerski, L. (deposition date: 2010-05-07, release date: 2011-06-01, Last modification date: 2011-07-13)
Primary citation
Borowicz, P.,Mikolajczyk, J.,Bocian, W.,Sitkowski, J.,Bednarek, E.,Jaworska, D.,Blazej, S.,Bogiel, M.,Mikiewicz-Sygula, D.,Kurzynoga, D.,Kozerski, L.
Novel recombinant insulin analogue with flexible C - terminus in B chain. NMR structure of biosynthetic engineered A22G-B31K-B32R human insulin monomer in water /acetonitrile solution.
To be Published,
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers00.5%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

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