NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures

Summary for 2L1Y

Related3OAL 3OB3 3OB5 2L1Z 2L1Y
DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordshormone, human insulin, mutant
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5845.7
Wan, Z.L.,Hua, Q.X.,Huang, K.,Hu, S.Q.,Philips, N.B.,Katsoyannis, J.W.,Weiss, M.A. (deposition date: 2010-08-09, release date: 2011-08-31)
Primary citation
Wan, Z.L.,Hua, Q.X.,Huang, K.,Hu, S.Q.,Philips, N.B.,Whittaker, J.,Katsoyannis, P.G.,Weiss, M.A.
Chiral Protein Engineering and its Application in G Health
To be Published,
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers73 6.0% 34.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
PDB entries from 2020-10-21