2KJU
NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures
Summary for 2KJU
Entry DOI | 10.2210/pdb2kju/pdb |
Related | 2KJJ |
Descriptor | Insulin (2 entities in total) |
Functional Keywords | hormone, human insulin, mutant, fibrillation, stability, carbohydrate metabolism, cleavage on pair of basic residues, disulfide bond, glucose metabolism, secreted, diabetes mellitus, disease mutation, pharmaceutical, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5794.59 |
Authors | Hua, Q.X.,Huang, K.,Hu, S.Q.,Katsoyanni, P.,Weiss, M.A. (deposition date: 2009-06-10, release date: 2010-06-16, Last modification date: 2021-10-13) |
Primary citation | Hua, Q.X.,Huang, K.,Hu, S.Q.,Katsoyanni, P.,Weiss, M.A. Acceleration of Protein Fibrillation by Chiral Destabilization of Beta-Turn To be Published, |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report