3I08
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3GE2
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![BU of 3ge2 by Molmil](/molmil-images/mine/3ge2) | Crystal structure of putative lipoprotein SP_0198 from Streptococcus pneumoniae | 分子名称: | CHLORIDE ION, GLYCEROL, Lipoprotein, ... | 著者 | Kim, Y, Zhang, R, Joachimiak, G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-02-24 | 公開日 | 2009-03-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | Crystal Structure of Putative Lipoprotein SP_0198 from Streptococcus pneumoniae To be Published
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3IMV
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3IOH
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![BU of 3ioh by Molmil](/molmil-images/mine/3ioh) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) | 分子名称: | GLYCEROL, Histo-blood group ABO system transferase | 著者 | Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K. | 登録日 | 2009-08-14 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat.Chem.Biol., 6, 2010
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3IPQ
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![BU of 3ipq by Molmil](/molmil-images/mine/3ipq) | X-ray structure of GW3965 synthetic agonist bound to the LXR-alpha | 分子名称: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | 登録日 | 2009-08-18 | 公開日 | 2010-06-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling. J.Mol.Biol., 399, 2010
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2WM9
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2WQO
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![BU of 2wqo by Molmil](/molmil-images/mine/2wqo) | STRUCTURE OF NEK2 BOUND TO THE AMINOPYRIDINE CCT241950 | 分子名称: | 4-[2-AMINO-5-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-3-YL]BENZOIC ACID, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 | 著者 | Mas-Droux, C, Bayliss, R. | 登録日 | 2009-08-24 | 公開日 | 2009-12-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.167 Å) | 主引用文献 | An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9. Mol.Cell, 36, 2009
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3ERQ
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3IV1
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![BU of 3iv1 by Molmil](/molmil-images/mine/3iv1) | Coiled-coil domain of tumor susceptibility gene 101 | 分子名称: | CHLORIDE ION, SULFATE ION, Tumor susceptibility gene 101 protein | 著者 | Neculai, D, Avvakumov, G.V, Wernimont, A.K, Xue, S, Walker, J.R, Li, Y, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-08-31 | 公開日 | 2009-11-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Coiled-Coil Domain of Human Tsg101 To be Published
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2WIP
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![BU of 2wip by Molmil](/molmil-images/mine/2wip) | STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1-METHYL-4,5-DIHYDRO- 1H-PYRAZOLO[4,3-H] QUINAZOLINE-3-CARBOXYLIC ACID | 分子名称: | 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid, CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, ... | 著者 | Brasca, M.G, Amboldi, N, Ballinari, D, Cameron, A.D, Casale, E, Cervi, G, Colombo, M, Colotta, F, Croci, V, Dalessio, R, Fiorentini, F, Isacchi, A, Mercurio, C, Moretti, W, Panzeri, A, Pastori, W, Pevarello, P, Quartieri, F, Roletto, F, Traquandi, G, Vianello, P, Vulpetti, A, Ciomei, M. | 登録日 | 2009-05-14 | 公開日 | 2009-07-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Identification of N,1,4,4-Tetramethyl-8-{[4-(4-Methylpiperazin-1-Yl)Phenyl]Amino}-4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline-3-Carboxamide (Pha-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor. J.Med.Chem., 52, 2009
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2WIF
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![BU of 2wif by Molmil](/molmil-images/mine/2wif) | AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Carletti, E, Aurbek, N, Gillon, E, Loiodice, M, Nicolet, Y, Fontecilla, J, Masson, P, Thiermann, H, Nachon, F, Worek, F. | 登録日 | 2009-05-11 | 公開日 | 2009-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. Biochem. J., 421, 2009
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2WKL
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![BU of 2wkl by Molmil](/molmil-images/mine/2wkl) | Velaglucerase alfa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCOSYLCERAMIDASE, ... | 著者 | Brumshtein, B, Salinas, P, Peterson, B, Chan, V, Silman, I, Sussman, J.L, Savickas, P.J, Robinson, G.S, Futerman, A.H. | 登録日 | 2009-06-15 | 公開日 | 2009-09-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Characterization of Gene-Activated Human Acid-Beta-Glucosidase: Crystal Structure, Glycan Composition and Internalization Into Macrophages. Glycobiology, 20, 2010
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2WIG
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![BU of 2wig by Molmil](/molmil-images/mine/2wig) | NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Carletti, E, Aurbek, N, Gillon, E, Loiodice, M, Nicolet, Y, Fontecilla, J, Masson, P, Thiermann, H, Nachon, F, Worek, F. | 登録日 | 2009-05-11 | 公開日 | 2009-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. Biochem. J., 421, 2009
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2WJW
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![BU of 2wjw by Molmil](/molmil-images/mine/2wjw) | Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 1.8 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | 著者 | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | 登録日 | 2009-06-01 | 公開日 | 2009-08-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors. J.Mol.Biol., 392, 2009
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3LHJ
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![BU of 3lhj by Molmil](/molmil-images/mine/3lhj) | Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor. | 分子名称: | Mitogen-activated protein kinase 14, N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide | 著者 | Mohr, C, Jordan, S. | 登録日 | 2010-01-22 | 公開日 | 2010-04-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase. J.Med.Chem., 53, 2010
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3LFS
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![BU of 3lfs by Molmil](/molmil-images/mine/3lfs) | Crystal structure of CDK2 with SAR37, an aminoindazole type inhibitor | 分子名称: | Cell division protein kinase 2, N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | 著者 | Dreyer, M.K, Wendt, K.U, Schimanski-Breves, S, Loenze, P. | 登録日 | 2010-01-18 | 公開日 | 2010-03-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg.Med.Chem.Lett., 20, 2010
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3EDX
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![BU of 3edx by Molmil](/molmil-images/mine/3edx) | Crystal structure of the W215A/E217A mutant of murine thrombin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Thrombin heavy chain, ... | 著者 | Gandhi, P.S, Page, M.J, Chen, Z, Bush-pelc, L, Di Cera, E. | 登録日 | 2008-09-03 | 公開日 | 2009-07-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular Basis for the Kinetic Differences of the W215A/E217A Mutant of Human and Murine Thrombin To be Published
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3EP5
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![BU of 3ep5 by Molmil](/molmil-images/mine/3ep5) | Human AdoMetDC E178Q mutant with no putrescine bound | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ... | 著者 | Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. | 登録日 | 2008-09-29 | 公開日 | 2008-12-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47, 2008
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2WVR
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![BU of 2wvr by Molmil](/molmil-images/mine/2wvr) | Human Cdt1:Geminin complex | 分子名称: | DNA REPLICATION FACTOR CDT1, GEMININ | 著者 | De Marco, V, Perrakis, A. | 登録日 | 2009-10-19 | 公開日 | 2009-10-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing. Proc.Natl.Acad.Sci.USA, 106, 2009
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2WJ7
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![BU of 2wj7 by Molmil](/molmil-images/mine/2wj7) | human alphaB crystallin | 分子名称: | ALPHA-CRYSTALLIN B CHAIN | 著者 | Naylor, C.E, Bagneris, C, Bateman, O.A, Cronin, N, Keep, N.H, Slingsby, C. | 登録日 | 2009-05-22 | 公開日 | 2009-08-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.631 Å) | 主引用文献 | Crystal Structures of Alpha-Crystallin Domain Dimers of Alphab-Crystallin and Hsp20. J.Mol.Biol., 392, 2009
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3LMP
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![BU of 3lmp by Molmil](/molmil-images/mine/3lmp) | Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator | 分子名称: | (9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-N-(1-naphthylmethyl)-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide, Peptide of Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | 著者 | Matsui, Y, Hanzawa, H. | 登録日 | 2010-01-31 | 公開日 | 2010-04-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives Bioorg.Med.Chem.Lett., 20, 2010
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3EIM
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3EP6
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![BU of 3ep6 by Molmil](/molmil-images/mine/3ep6) | Human AdoMetDC D174N mutant complexed with S-Adenosylmethionine methyl ester and no putrescine bound | 分子名称: | PYRUVIC ACID, S-ADENOSYLMETHIONINE METHYL ESTER, S-adenosylmethionine decarboxylase alpha chain, ... | 著者 | Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. | 登録日 | 2008-09-29 | 公開日 | 2008-12-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47, 2008
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3EDY
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![BU of 3edy by Molmil](/molmil-images/mine/3edy) | Crystal Structure of the Precursor Form of Human Tripeptidyl-Peptidase 1 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Guhaniyogi, J, Sohar, I, Das, K, Lobel, P, Stock, A.M. | 登録日 | 2008-09-03 | 公開日 | 2008-11-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis J.Biol.Chem., 284, 2009
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3LPP
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![BU of 3lpp by Molmil](/molmil-images/mine/3lpp) | Crystal complex of N-terminal sucrase-isomaltase with kotalanol | 分子名称: | (1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2010-02-05 | 公開日 | 2010-03-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J.Biol.Chem., 285, 2010
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