Human Cdt1:Geminin complex

Summary for 2WVR

Related1UII 1T6F
DescriptorGEMININ, DNA REPLICATION FACTOR CDT1 (2 entities in total)
Functional Keywordsreplication, dna replication license, dna replication inhibitor, phosphoprotein, ubl conjugation, dna replication, dna-binding, polymorphism, proto-oncogene, nucleus, cell cycle, acetylation, coiled coil
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus Q9H211
Total number of polymer chains3
Total molecular weight107733.75
De Marco, V.,Perrakis, A. (deposition date: 2009-10-19, release date: 2009-10-27, Last modification date: 2011-07-13)
Primary citation
De Marco, V.,Gillespie, P.J.,Li, A.,Karantzelis, N.,Christodoulou, E.,Klompmaker, R.,Van Gerwen, S.,Fish, A.,Petoukhov, M.V.,Iliou, M.S.,Lygerou, Z.,Medema, R.H.,Blow, J.J.,Svergun, D.I.,Taraviras, S.,Perrakis, A.
Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing.
Proc.Natl.Acad.Sci.USA, 106:19807-, 2009
PubMed: 19906994 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.0905281106
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.30019 4.2% 7.2% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02